Panoramic ultrasound

a novel and valid tool for monitoring change in muscle mass

Jessica M. Scott, David S. Martin, Robert Ploutz-Snyder, Timothy Matz, Timothy Caine, Meghan Downs, Kyle J Hackney, Roxanne Buxton, Jeffrey W. Ryder, Lori Ploutz-Snyder

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Background: The strong link between reduced muscle mass and morbidity and mortality highlights the urgent need for simple techniques that can monitor change in skeletal muscle cross-sectional area (CSA). Our objective was to examine the validity of panoramic ultrasound to detect change in quadriceps and gastrocnemius size in comparison with magnetic resonance imaging (MRI) in subjects randomized to 70 days of bed rest (BR) with or without exercise. Methods: Panoramic ultrasound and MRI images of the quadriceps and gastrocnemius muscles were acquired on the right leg of 27 subjects (26 male, 1 female; age: 34.6 ± 7.8 years; body mass: 77.5 ± 10.0 kg; body mass index: 24.2 ± 2.8 kg/m2; height: 179.1 ± 6.9 cm) before (BR-6), during (BR3, 7, 11, 15, 22, 29, 36, 53, 69), and after (BR+3, +6, +10) BR. Validity of panoramic ultrasound to detect change in muscle CSA was assessed by Bland–Altman plots, Lin's concordance correlation coefficient (CCC), sensitivity, specificity, positive predictive value, and negative predictive value. Results: Six hundred ninety-eight panoramic ultrasound CSA and 698 MRI CSA measurements were assessed. Concordance between ultrasound and MRI was excellent in the quadriceps (CCC: 0.78; P < 0.0001), whereas there was poor concordance in the gastrocnemius (CCC: 0.37; P < 0.0006). Compared with MRI, panoramic ultrasound demonstrated high accuracy in detecting quadriceps atrophy and hypertrophy (sensitivity: 73.7%; specificity: 74.2%) and gastrocnemius atrophy (sensitivity: 83.1%) and low accuracy in detecting gastrocnemius hypertrophy (specificity: 33.0%). Conclusions: Panoramic ultrasound imaging is a valid tool for monitoring quadriceps muscle atrophy and hypertrophy and for detecting gastrocnemius atrophy.

Original languageEnglish (US)
Pages (from-to)475-481
Number of pages7
JournalJournal of Cachexia, Sarcopenia and Muscle
Volume8
Issue number3
DOIs
StatePublished - Jun 1 2017
Externally publishedYes

Fingerprint

Bed Rest
Magnetic Resonance Imaging
Muscles
Hypertrophy
Atrophy
Quadriceps Muscle
Skeletal Muscle
Muscular Atrophy
Ultrasonography
Leg
Body Mass Index
Morbidity
Sensitivity and Specificity
Mortality

Keywords

  • Atrophy
  • Disuse
  • Hypertrophy
  • Magnetic resonance imaging
  • Panoramic ultrasound

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Physiology (medical)

Cite this

Scott, J. M., Martin, D. S., Ploutz-Snyder, R., Matz, T., Caine, T., Downs, M., ... Ploutz-Snyder, L. (2017). Panoramic ultrasound: a novel and valid tool for monitoring change in muscle mass. Journal of Cachexia, Sarcopenia and Muscle, 8(3), 475-481. https://doi.org/10.1002/jcsm.12172

Panoramic ultrasound : a novel and valid tool for monitoring change in muscle mass. / Scott, Jessica M.; Martin, David S.; Ploutz-Snyder, Robert; Matz, Timothy; Caine, Timothy; Downs, Meghan; Hackney, Kyle J; Buxton, Roxanne; Ryder, Jeffrey W.; Ploutz-Snyder, Lori.

In: Journal of Cachexia, Sarcopenia and Muscle, Vol. 8, No. 3, 01.06.2017, p. 475-481.

Research output: Contribution to journalArticle

Scott, JM, Martin, DS, Ploutz-Snyder, R, Matz, T, Caine, T, Downs, M, Hackney, KJ, Buxton, R, Ryder, JW & Ploutz-Snyder, L 2017, 'Panoramic ultrasound: a novel and valid tool for monitoring change in muscle mass', Journal of Cachexia, Sarcopenia and Muscle, vol. 8, no. 3, pp. 475-481. https://doi.org/10.1002/jcsm.12172
Scott, Jessica M. ; Martin, David S. ; Ploutz-Snyder, Robert ; Matz, Timothy ; Caine, Timothy ; Downs, Meghan ; Hackney, Kyle J ; Buxton, Roxanne ; Ryder, Jeffrey W. ; Ploutz-Snyder, Lori. / Panoramic ultrasound : a novel and valid tool for monitoring change in muscle mass. In: Journal of Cachexia, Sarcopenia and Muscle. 2017 ; Vol. 8, No. 3. pp. 475-481.
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AU - Matz, Timothy

AU - Caine, Timothy

AU - Downs, Meghan

AU - Hackney, Kyle J

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