Oxacycle synthesis via intramolecular reaction of carbanions and peroxides

Rachel Willand-Charnley, Benjamin W. Puffer, Patrick H. Dussault

Research output: Contribution to journalArticle

29 Scopus citations

Abstract

The intramolecular reaction of dialkyl peroxides with carbanions, generated via chemoselective metal-heteroatom exchange or deprotonation, provides a new approach to cyclic ethers. Applied in tandem with C-C bond formation, the strategy enables a one-step annelation to form oxaospirocycles.

Original languageEnglish (US)
Pages (from-to)5821-5823
Number of pages3
JournalJournal of the American Chemical Society
Volume136
Issue number16
DOIs
Publication statusPublished - Apr 23 2014

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ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

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