Outcomes for COPD pharmacological trials: From lung function to biomarkers

M. Cazzola, W. MacNee, F. J. Martinez, K. F. Rabe, L. G. Franciosi, P. J. Barnes, V. Brusasco, P. S. Burge, P. M.A. Calverley, B. R. Celli, P. W. Jones, D. A. Mahler, B. Make, M. Miravitlles, C. P. Page, P. Palange, D. Parr, M. Pistolesi, S. I. Rennard, M. P. Rutten-van MölkenR. Stockley, S. D. Sullivan, J. A. Wedzicha, E. F. Wouters

Research output: Contribution to journalReview article

597 Citations (Scopus)

Abstract

The American Thoracic Society/European Respiratory Society jointly created a Task Force on "Outcomes for COPD pharmacological trials: from lung function to biomarkers" to inform the chronic obstructive pulmonary disease research community about the possible use and limitations of current outcomes and markers when evaluating the impact of a pharmacological therapy. Based on their review of the published literature, the following document has been prepared with individual sections that address specific outcomes and markers, and a final section that summarises their recommendations. Copyright

Original languageEnglish (US)
Pages (from-to)416-468
Number of pages53
JournalEuropean Respiratory Journal
Volume31
Issue number2
DOIs
StatePublished - Feb 1 2008

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Chronic Obstructive Pulmonary Disease
Biomarkers
Pharmacology
Lung
Advisory Committees
Research
Therapeutics

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

Cazzola, M., MacNee, W., Martinez, F. J., Rabe, K. F., Franciosi, L. G., Barnes, P. J., ... Wouters, E. F. (2008). Outcomes for COPD pharmacological trials: From lung function to biomarkers. European Respiratory Journal, 31(2), 416-468. https://doi.org/10.1183/09031936.00099306

Outcomes for COPD pharmacological trials : From lung function to biomarkers. / Cazzola, M.; MacNee, W.; Martinez, F. J.; Rabe, K. F.; Franciosi, L. G.; Barnes, P. J.; Brusasco, V.; Burge, P. S.; Calverley, P. M.A.; Celli, B. R.; Jones, P. W.; Mahler, D. A.; Make, B.; Miravitlles, M.; Page, C. P.; Palange, P.; Parr, D.; Pistolesi, M.; Rennard, S. I.; Rutten-van Mölken, M. P.; Stockley, R.; Sullivan, S. D.; Wedzicha, J. A.; Wouters, E. F.

In: European Respiratory Journal, Vol. 31, No. 2, 01.02.2008, p. 416-468.

Research output: Contribution to journalReview article

Cazzola, M, MacNee, W, Martinez, FJ, Rabe, KF, Franciosi, LG, Barnes, PJ, Brusasco, V, Burge, PS, Calverley, PMA, Celli, BR, Jones, PW, Mahler, DA, Make, B, Miravitlles, M, Page, CP, Palange, P, Parr, D, Pistolesi, M, Rennard, SI, Rutten-van Mölken, MP, Stockley, R, Sullivan, SD, Wedzicha, JA & Wouters, EF 2008, 'Outcomes for COPD pharmacological trials: From lung function to biomarkers', European Respiratory Journal, vol. 31, no. 2, pp. 416-468. https://doi.org/10.1183/09031936.00099306
Cazzola M, MacNee W, Martinez FJ, Rabe KF, Franciosi LG, Barnes PJ et al. Outcomes for COPD pharmacological trials: From lung function to biomarkers. European Respiratory Journal. 2008 Feb 1;31(2):416-468. https://doi.org/10.1183/09031936.00099306
Cazzola, M. ; MacNee, W. ; Martinez, F. J. ; Rabe, K. F. ; Franciosi, L. G. ; Barnes, P. J. ; Brusasco, V. ; Burge, P. S. ; Calverley, P. M.A. ; Celli, B. R. ; Jones, P. W. ; Mahler, D. A. ; Make, B. ; Miravitlles, M. ; Page, C. P. ; Palange, P. ; Parr, D. ; Pistolesi, M. ; Rennard, S. I. ; Rutten-van Mölken, M. P. ; Stockley, R. ; Sullivan, S. D. ; Wedzicha, J. A. ; Wouters, E. F. / Outcomes for COPD pharmacological trials : From lung function to biomarkers. In: European Respiratory Journal. 2008 ; Vol. 31, No. 2. pp. 416-468.
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