Abstract
An epidemiologic investigation was conducted to characterize and evaluate the possibility of a viral aetiology of an outbreak of acute vertigo in Hot Springs County, Wyoming, during autumn 1992. Case-finding identified Hot Springs County residents who sought medical attention for new onset vertigo during 1 August, 1992-31 January 1993. Thirty-five case-patients and 61 matched controls were interviewed and serum specimens were obtained during January 1993. Case-patients were more likely than controls to report symptoms (e.g. fatigue, sore throat, fever, diarrhoea) of antecedent acute illness. Case-patients did not have a significantly greater prevalence or mean titre of IgG antibodies to respiratory syncytial virus, parainfluenza viruses, Epstein-Barr virus, and cytomegalovirus than controls. Serologic evidence of recent enterovirus infection (IgM antibodies) was found for 74% of case-patients compared with 54% of controls (P < 0.05), suggesting a possible association between vertigo and enterovirus infection. Future studies are needed to define the role of enteroviruses in innerear diseases.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 149-157 |
| Number of pages | 9 |
| Journal | Epidemiology and Infection |
| Volume | 117 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 1 1996 |
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ASJC Scopus subject areas
- Epidemiology
- Infectious Diseases
Cite this
Outbreak of vertigo in Wyoming : Possible role of an enterovirus infection. / Simonsen, L.; Khan, A. S.; Gary, H. E.; Hanson, C.; Pallansch, M. A.; Music, S.; Holman, R. C.; Stewart, J. A.; Erdman, D. D.; Arden, N. H.; Arenberg, I. K.; Schonberger, L. B.
In: Epidemiology and Infection, Vol. 117, No. 1, 01.01.1996, p. 149-157.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Outbreak of vertigo in Wyoming
T2 - Possible role of an enterovirus infection
AU - Simonsen, L.
AU - Khan, A. S.
AU - Gary, H. E.
AU - Hanson, C.
AU - Pallansch, M. A.
AU - Music, S.
AU - Holman, R. C.
AU - Stewart, J. A.
AU - Erdman, D. D.
AU - Arden, N. H.
AU - Arenberg, I. K.
AU - Schonberger, L. B.
PY - 1996/1/1
Y1 - 1996/1/1
N2 - An epidemiologic investigation was conducted to characterize and evaluate the possibility of a viral aetiology of an outbreak of acute vertigo in Hot Springs County, Wyoming, during autumn 1992. Case-finding identified Hot Springs County residents who sought medical attention for new onset vertigo during 1 August, 1992-31 January 1993. Thirty-five case-patients and 61 matched controls were interviewed and serum specimens were obtained during January 1993. Case-patients were more likely than controls to report symptoms (e.g. fatigue, sore throat, fever, diarrhoea) of antecedent acute illness. Case-patients did not have a significantly greater prevalence or mean titre of IgG antibodies to respiratory syncytial virus, parainfluenza viruses, Epstein-Barr virus, and cytomegalovirus than controls. Serologic evidence of recent enterovirus infection (IgM antibodies) was found for 74% of case-patients compared with 54% of controls (P < 0.05), suggesting a possible association between vertigo and enterovirus infection. Future studies are needed to define the role of enteroviruses in innerear diseases.
AB - An epidemiologic investigation was conducted to characterize and evaluate the possibility of a viral aetiology of an outbreak of acute vertigo in Hot Springs County, Wyoming, during autumn 1992. Case-finding identified Hot Springs County residents who sought medical attention for new onset vertigo during 1 August, 1992-31 January 1993. Thirty-five case-patients and 61 matched controls were interviewed and serum specimens were obtained during January 1993. Case-patients were more likely than controls to report symptoms (e.g. fatigue, sore throat, fever, diarrhoea) of antecedent acute illness. Case-patients did not have a significantly greater prevalence or mean titre of IgG antibodies to respiratory syncytial virus, parainfluenza viruses, Epstein-Barr virus, and cytomegalovirus than controls. Serologic evidence of recent enterovirus infection (IgM antibodies) was found for 74% of case-patients compared with 54% of controls (P < 0.05), suggesting a possible association between vertigo and enterovirus infection. Future studies are needed to define the role of enteroviruses in innerear diseases.
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UR - http://www.scopus.com/inward/citedby.url?scp=9444277213&partnerID=8YFLogxK
U2 - 10.1017/S0950268800001254
DO - 10.1017/S0950268800001254
M3 - Article
C2 - 8760963
AN - SCOPUS:9444277213
VL - 117
SP - 149
EP - 157
JO - Epidemiology and Infection
JF - Epidemiology and Infection
SN - 0950-2688
IS - 1
ER -