36 Citations (Scopus)

Abstract

The past year has seen advances in our understanding of the mechanisms that control the expression of organ-specific autoimmunity. Attempts to develop therapeutic strategies for the prevention of autoimmune disease have largely been based on deviation of the T-cell response away from an autoaggressive, pro-inflammatory Th 1 response. Manipulation of the cytokine environment at the site of antigen uptake or presentation, the source of endogenous antigen, costimulatory molecules or peptides processed and presented has yielded interesting results.

Original languageEnglish (US)
Pages (from-to)863-871
Number of pages9
JournalCurrent Opinion in Immunology
Volume9
Issue number6
DOIs
StatePublished - Dec 1997

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Autoimmunity
Antigens
Autoimmune Diseases
Cytokines
T-Lymphocytes
Peptides
Therapeutics

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

Cite this

Organ-specific autoimmunity. / King, Cecile; Sarvetnick, Nora.

In: Current Opinion in Immunology, Vol. 9, No. 6, 12.1997, p. 863-871.

Research output: Contribution to journalArticle

King, Cecile ; Sarvetnick, Nora. / Organ-specific autoimmunity. In: Current Opinion in Immunology. 1997 ; Vol. 9, No. 6. pp. 863-871.
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