Oral complications associated with bone marrow transplantation in a pediatrie population

R. J. Berkowitz, J. Crock, R. Strickland, E. M. Gordon, S. Strandjord, Peter Felix Coccia

Research output: Contribution to journalArticle

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Abstract

The effect of dental evaluation and treatment prior to bone marrow transplantation in 11 pediatrie patients was assessed. Oral complications associated with marrow ablative therapy and the immediate posttransplant period (Days 0–35) were also studied. Oral complications during marrow ablative therapy included: xerostomia (2/11 patients) and parotitis (1/11 patients). Oral complications in the immediate posttransplant period (Days 0–35) included: mucositis (11/11 patients); moniliasis (9/11 patients); and stomatitis associated with acute G.V.H.D. (3/9 patients receiving allogeneic marrow transplants). The onset of the mucositis in the posttransplant period usually occurred at the nadir of the white blood cell count and resolved when the absolute neutrophil count was approximately 500/m3. The onset of moniliasis in the posttransplant period was usually 1–2 days after the onset of the mucositis. Resolution of the moniliasis usually paralleled resolution of the mucositis. No patient developed an infectious and/or hemorrhagic complication of odontogenic origin.

Original languageEnglish (US)
Pages (from-to)53-57
Number of pages5
JournalAmerican Journal of Pediatric Hematology/Oncology
Volume5
Issue number1
StatePublished - Jan 1 1983

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Bone Marrow Transplantation
Mucositis
Candidiasis
Population
Bone Marrow
Parotitis
Xerostomia
Stomatitis
Leukocyte Count
Tooth
Neutrophils
Therapeutics
Transplants

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Hematology
  • Oncology

Cite this

Berkowitz, R. J., Crock, J., Strickland, R., Gordon, E. M., Strandjord, S., & Coccia, P. F. (1983). Oral complications associated with bone marrow transplantation in a pediatrie population. American Journal of Pediatric Hematology/Oncology, 5(1), 53-57.

Oral complications associated with bone marrow transplantation in a pediatrie population. / Berkowitz, R. J.; Crock, J.; Strickland, R.; Gordon, E. M.; Strandjord, S.; Coccia, Peter Felix.

In: American Journal of Pediatric Hematology/Oncology, Vol. 5, No. 1, 01.01.1983, p. 53-57.

Research output: Contribution to journalArticle

Berkowitz, RJ, Crock, J, Strickland, R, Gordon, EM, Strandjord, S & Coccia, PF 1983, 'Oral complications associated with bone marrow transplantation in a pediatrie population', American Journal of Pediatric Hematology/Oncology, vol. 5, no. 1, pp. 53-57.
Berkowitz RJ, Crock J, Strickland R, Gordon EM, Strandjord S, Coccia PF. Oral complications associated with bone marrow transplantation in a pediatrie population. American Journal of Pediatric Hematology/Oncology. 1983 Jan 1;5(1):53-57.
Berkowitz, R. J. ; Crock, J. ; Strickland, R. ; Gordon, E. M. ; Strandjord, S. ; Coccia, Peter Felix. / Oral complications associated with bone marrow transplantation in a pediatrie population. In: American Journal of Pediatric Hematology/Oncology. 1983 ; Vol. 5, No. 1. pp. 53-57.
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