Opioid antagonists. I

Pharmacology and rationale for use in treating self-injury

Yadhu N. Singh, Robert W. Ricketts, Cynthia R Ellis, Nirhay N. Singh

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Endogenous opioid peptides have been implicated in the genesis and maintenance of self-injurious behavior. This paper presents an overview of the basic pharmacology of opioid peptides and opioid antagonists and briefly outlines the rationale for using these agents to treat self-injury in individuals with mental retardation. The basic assumption is that self-injury is related to the endogenous opioid system, with two, nonexclusive mechanisms having been postulated that may account for this behavior.

Original languageEnglish (US)
Pages (from-to)5-15
Number of pages11
JournalJournal of Developmental and Physical Disabilities
Volume5
Issue number1
DOIs
StatePublished - Mar 1 1993

Fingerprint

Opioid Peptides
Narcotic Antagonists
Pharmacology
Self-Injurious Behavior
Wounds and Injuries
Intellectual Disability
Opioid Analgesics

Keywords

  • opioid antagonists
  • pharmacology
  • self-injury

ASJC Scopus subject areas

  • Physical Therapy, Sports Therapy and Rehabilitation
  • Developmental and Educational Psychology

Cite this

Opioid antagonists. I : Pharmacology and rationale for use in treating self-injury. / Singh, Yadhu N.; Ricketts, Robert W.; Ellis, Cynthia R; Singh, Nirhay N.

In: Journal of Developmental and Physical Disabilities, Vol. 5, No. 1, 01.03.1993, p. 5-15.

Research output: Contribution to journalArticle

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