Ocular manifestations of subacute sclerosing panencephalitis

Kashif Janjua, Salman Sarwar, Yasir J. Sepah, Quan Dong Nguyen

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Subacute sclerosing panencephalitis (SSPE) is a progressively fatal degenerative disease of the central nervous system. It is a slow virus infection caused by a genetically altered form of the measles virus. SSPE has been reported from all parts of the world, but in the West it is considered a rare disease with fewer than ten cases per year reported in the United States. One in 100,000 people infected with measles are at risk. Billine et al. suggest that the risk of SSPE in the United States may be tenfold higher than originally estimated due to major resurgence of measles between 1989 and 1991. Widespread immunization has produced greater than 90 % reduction in the incidence of SSPE in developed nations. However, the annual incidence of SSPE is still quite high among developing countries. Saha et al. reported an annual incidence of 21 per million populations in India, in comparison with 2.4 per million populations in the Middle East. A higher incidence has been noted in boys (male/female ratio 3:1), although primary measles infection shows no such sex disparity.

Original languageEnglish (US)
Title of host publicationIntraocular Inflammation
PublisherSpringer Berlin Heidelberg
Pages1221-1226
Number of pages6
ISBN (Electronic)9783540753872
ISBN (Print)9783540753858
DOIs
StatePublished - Jan 1 2016

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Eye Manifestations
Subacute Sclerosing Panencephalitis
Measles
Incidence
Measles virus
Middle East
Virus Diseases
Rare Diseases
Developed Countries
Neurodegenerative Diseases
Population
Developing Countries
India
Immunization
Infection

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Janjua, K., Sarwar, S., Sepah, Y. J., & Nguyen, Q. D. (2016). Ocular manifestations of subacute sclerosing panencephalitis. In Intraocular Inflammation (pp. 1221-1226). Springer Berlin Heidelberg. https://doi.org/10.1007/978-3-540-75387-2_116

Ocular manifestations of subacute sclerosing panencephalitis. / Janjua, Kashif; Sarwar, Salman; Sepah, Yasir J.; Nguyen, Quan Dong.

Intraocular Inflammation. Springer Berlin Heidelberg, 2016. p. 1221-1226.

Research output: Chapter in Book/Report/Conference proceedingChapter

Janjua, K, Sarwar, S, Sepah, YJ & Nguyen, QD 2016, Ocular manifestations of subacute sclerosing panencephalitis. in Intraocular Inflammation. Springer Berlin Heidelberg, pp. 1221-1226. https://doi.org/10.1007/978-3-540-75387-2_116
Janjua K, Sarwar S, Sepah YJ, Nguyen QD. Ocular manifestations of subacute sclerosing panencephalitis. In Intraocular Inflammation. Springer Berlin Heidelberg. 2016. p. 1221-1226 https://doi.org/10.1007/978-3-540-75387-2_116
Janjua, Kashif ; Sarwar, Salman ; Sepah, Yasir J. ; Nguyen, Quan Dong. / Ocular manifestations of subacute sclerosing panencephalitis. Intraocular Inflammation. Springer Berlin Heidelberg, 2016. pp. 1221-1226
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