Nucleoside and nucleobase analog mutagens

Kazuo Negishi, Tadayashi Bessho, Hikoya Hayatsu

Research output: Contribution to journalReview article

17 Citations (Scopus)

Abstract

Compounds with structures close to those of normal nucleosides or nucleobases may be incorporated into cells and then become constituent of their DNA. Proliferation of such cells could yield mutants. In this article, the current status of studies on such nucleoside and nucleobase analogs is described. Base mispairing mechanisms for these analogs are discussed in light of recent biochemical and biophysical findings.

Original languageEnglish (US)
Pages (from-to)227-238
Number of pages12
JournalMutation Research/Reviews in Genetic Toxicology
Volume318
Issue number3
DOIs
StatePublished - Dec 1994

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Mutagens
Nucleosides
Cell Proliferation
DNA

ASJC Scopus subject areas

  • Toxicology
  • Genetics

Cite this

Nucleoside and nucleobase analog mutagens. / Negishi, Kazuo; Bessho, Tadayashi; Hayatsu, Hikoya.

In: Mutation Research/Reviews in Genetic Toxicology, Vol. 318, No. 3, 12.1994, p. 227-238.

Research output: Contribution to journalReview article

Negishi, Kazuo ; Bessho, Tadayashi ; Hayatsu, Hikoya. / Nucleoside and nucleobase analog mutagens. In: Mutation Research/Reviews in Genetic Toxicology. 1994 ; Vol. 318, No. 3. pp. 227-238.
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