2 Citations (Scopus)

Abstract

Paragangliomas associated with mutations of the SDHD gene can occasionally result in distant metastasis. Diagnosis can be difficult, and nuclear imaging is used to evaluate the case further. Not all tumors are alike; nuclear avidity may differ. We present a case in which metastatic paraganglioma caused by mutations of the SDHD gene was negative on 123I-metaiodobenzylguanidine scintigraphy and positive on 111In-labeled octreotide scintigraphy. This situation presents an opportunity for a novel therapeutic approach toward metastatic paraganglioma using targeted peptide receptor radionuclide therapy.

Original languageEnglish (US)
Pages (from-to)251-252
Number of pages2
JournalJournal of Nuclear Medicine Technology
Volume44
Issue number4
DOIs
StatePublished - Jan 1 2016

Fingerprint

Paraganglioma
Radionuclide Imaging
Mutation
Peptide Receptors
Radioisotopes
Genes
Neoplasm Metastasis
Therapeutics
Neoplasms

Keywords

  • Neuroendocrine tumor
  • Paraganglioma
  • Peptide receptor therapy

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging

Cite this

Nuclear imaging in metastatic paraganglioma. / Kedia, Rohit; Hansen, Neil J; Goldner, Whitney S.

In: Journal of Nuclear Medicine Technology, Vol. 44, No. 4, 01.01.2016, p. 251-252.

Research output: Contribution to journalArticle

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