Novel technologies for the prevention and treatment of dental caries

A patent survey

Fu Chen, Dong Wang

Research output: Contribution to journalReview article

42 Citations (Scopus)

Abstract

Importance of the field: Dental caries is one of the most common preventable childhood diseases; people are susceptible to this ailment throughout their lifetime. In the US, 90% of late adolescents and young adults have dental caries, while 94% of all dentate adults had evidence of treated or untreated coronal caries. Dental caries is often not self-limiting and without proper care can progress until the tooth is destroyed. Areas covered in this review: In this paper, the etiology of dental caries is briefly introduced. It is followed by a thorough review of patents and literatures on the recent development of various novel technologies for the prevention and treatment of dental caries. What the reader will gain: Recent advances in anti-plaque agents, including chemoprophylactic agents, antimicrobial peptides, vaccines, probiotics/replacement therapy and sugar substitutes, and remineralization agents including fluorides and casein phosphopeptides are analyzed. Take home massage: Both the discovery of new anti-caries agents and the development of dentotropic delivery systems will be the future focus of this research field.

Original languageEnglish (US)
Pages (from-to)681-694
Number of pages14
JournalExpert Opinion on Therapeutic Patents
Volume20
Issue number5
DOIs
StatePublished - May 1 2010

Fingerprint

Dental Caries
Technology
Therapeutics
Sweetening Agents
Phosphopeptides
Subunit Vaccines
Patents
Massage
Probiotics
Anti-Infective Agents
Caseins
Fluorides
Young Adult
Tooth
Surveys and Questionnaires
Research

Keywords

  • Antimicrobial
  • Dental caries
  • Drug delivery
  • Fluoride therapy
  • Sugar substitute

ASJC Scopus subject areas

  • Pharmacology
  • Drug Discovery

Cite this

Novel technologies for the prevention and treatment of dental caries : A patent survey. / Chen, Fu; Wang, Dong.

In: Expert Opinion on Therapeutic Patents, Vol. 20, No. 5, 01.05.2010, p. 681-694.

Research output: Contribution to journalReview article

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