Non-nutritive sucking recorded in utero via fetal magnetography

E. A. Popescu, M. Popescu, J. Wang, S. M. Barlow, K. M. Gustafson

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Several studies in term and pre-term infants have investigated the rhythmic pattern of non-nutritive sucking (NNS) indicating correlations between the quantitative measures derived from sucking pressure variation and/or electromyographic (EMG) recordings and a range of factors that include age, perinatal stress and sequelae. In the human fetus, NNS has been reported from 13 weeks of gestation and has been studied using real-time Doppler ultrasonography exclusively. The present study indicates that NNS in fetus can be reliably recorded and quantified using non-invasive biomagnetic measurements that have been recently introduced as an investigational tool for the assessment of fetal neurophysiologic development. We show that source separation techniques, such as independent component analysis, applied to the high-resolution multichannel recordings allow the segregation of an explicit waveform that represents the biomagnetic equivalent of the ororhythmic sucking pressure variation or EMG signal recorded in infants. This enables the morphological study of NNS patterning over different temporal scales, from the global quantitative measures to the within burst fine structure characterization, in correlation with the fetal cardiac rhythm.

Original languageEnglish (US)
Pages (from-to)127-139
Number of pages13
JournalPhysiological Measurement
Volume29
Issue number1
DOIs
StatePublished - Jan 1 2008

Fingerprint

Fetus
Ultrasonography
Pressure
Source separation
Doppler Ultrasonography
Age Factors
Independent component analysis
Fetal Development
Pregnancy

Keywords

  • Fetal biomagnetometry
  • Fetal non-nutritive sucking
  • Independent component analysis (ICA)
  • Non-invasive fetal monitoring

ASJC Scopus subject areas

  • Biophysics
  • Physiology
  • Biomedical Engineering
  • Physiology (medical)

Cite this

Non-nutritive sucking recorded in utero via fetal magnetography. / Popescu, E. A.; Popescu, M.; Wang, J.; Barlow, S. M.; Gustafson, K. M.

In: Physiological Measurement, Vol. 29, No. 1, 01.01.2008, p. 127-139.

Research output: Contribution to journalArticle

Popescu, E. A. ; Popescu, M. ; Wang, J. ; Barlow, S. M. ; Gustafson, K. M. / Non-nutritive sucking recorded in utero via fetal magnetography. In: Physiological Measurement. 2008 ; Vol. 29, No. 1. pp. 127-139.
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