Non-Hodgkin lymphoma of bone in an HIV-infected patient from Argentina

Uriel Sandkovsky, Pablo F. Martin, Emiliano Bissio

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Introduction: Human immunodeficiency virus (HIV)-infected patients are at higher risk for development of Non-Hodgkin's lymphoma (NHL). The estimated incidence of NHL in patients with acquired immunodeficiency syndrome (AIDS) is much higher when compared to the general population. Most AIDS-associated NHL are of intermediate- or high-grade B-cell type and involve extranodal sites more frequently. The most common sites are the central nervous system (CNS), gastrointestinal tract, liver, bone marrow and soft tissues. Methodology: We describe a 42-year-old male with risk factors for HIV infection who presented with left leg pain and an osteolytic lesion of the left medial tibia. He was subsequently diagnosed with HIV disease and an open biopsy of his left tibia established the diagnosis of NHL. Results: After starting antiretroviral therapy followed by chemotherapy he achieved remission. Conclusion: Bone lymphomas account for 3% of malignant bone tumors and 4-7% of all extranodal sites. NHL of bone has been infrequently described in patients with AIDS. To our knowledge, this is the first report of NHL of the bone in Argentina.

Original languageEnglish (US)
Pages (from-to)815-819
Number of pages5
JournalJournal of Infection in Developing Countries
Volume5
Issue number11
DOIs
StatePublished - Jan 1 2011

Fingerprint

Argentina
Non-Hodgkin's Lymphoma
HIV
Bone and Bones
Acquired Immunodeficiency Syndrome
Virus Diseases
Tibia
Gastrointestinal Tract
Lymphoma
Leg
B-Lymphocytes
Central Nervous System
Bone Marrow
Biopsy
Drug Therapy
Pain
Liver
Incidence
Population
Neoplasms

Keywords

  • AIDS
  • AIDS-related lymphoma
  • HIV infection
  • Non-Hodgkin lymphoma

ASJC Scopus subject areas

  • Parasitology
  • Microbiology
  • Infectious Diseases
  • Virology

Cite this

Non-Hodgkin lymphoma of bone in an HIV-infected patient from Argentina. / Sandkovsky, Uriel; Martin, Pablo F.; Bissio, Emiliano.

In: Journal of Infection in Developing Countries, Vol. 5, No. 11, 01.01.2011, p. 815-819.

Research output: Contribution to journalArticle

Sandkovsky, Uriel ; Martin, Pablo F. ; Bissio, Emiliano. / Non-Hodgkin lymphoma of bone in an HIV-infected patient from Argentina. In: Journal of Infection in Developing Countries. 2011 ; Vol. 5, No. 11. pp. 815-819.
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