Enfermedad de hígado graso no alcohólico (EHGNA): Revisión y puesta al día. Grupo de trabajo de la sociedad latinoamericana de gastroenterología hepatología y nutrición pediátrica (SLAGHNP)

Translated title of the contribution: Non-alcoholic fatty liver disease (NAFLD): Review and update. Working group of the latinamerican society of pediatric gastroenterology, hepatology and nutrition (LASPGHAN)

Fernando Sarmiento Quintero, Verónica Botero, Daniel D. Agostino, Laura Delgado Carbajal, María Rita Dewaele Olivera, Celina Guzmán, Edgar Játiva, Graciela Teresita Martin, Milton Mejía Castro, Lourdes Ortiz Paranza, María Cecilia Pabón Uego, Luis Peña Quintana, Ruben Quiros, Nelson Ramírez Rodríguez, Margarita Ramonet, Juan Rivera Medina, Marta Sanabria, Claudia P. Sánchez Franco, Lidia Patricia Valdiviezo, Cristina Galoppo

Research output: Contribution to journalReview article

Abstract

Summary Along with obesity, non-alcoholic fatty liver disease, and its progression to esteatohepatitis, have become the most frequent liver disease among children and teenagers. Since cirrhosis could be an outcome of this condition, it is urgent to test for it in overweight and obese patients. Objectives. To compile in a single article strategies for clinical coaching and handling of children with this condition. On the basis of this revision, to promote research projects. Methods. SLAGHNP/LAPSGHAN, under responsibility and supervision of an editor/coordinator who chose contents and references with the best evidence, called its associates to perform this revision, after which edition and unification of the contents proposed. Results. The severity of EHGNA/ EHNA is established as a new infant liver disease and the lack of information on it in Latin America is noted unlike the United State, where its status as the most prevalent hepatopathy among children has been already established. Usefulness of blood chemistry tests and images is emphasized; although it has not been established when it should be recommended, it is clear liver biopsy is the gold standard for detecting the disease. Conclusions. It is important to start in Latin America research and follow-up programs on this disease, whose rapid progression will be continentwise a public health concern in the near future. A latin american register should be started under leadership of SLAGHNP/LAPSGHAN to establish this liver disease's epidemiology, establish a clinical diagnosis and choose adequate complimentary tests to confirm diagnosis.

Original languageSpanish
Pages (from-to)246-264
Number of pages19
JournalActa Gastroenterologica Latinoamericana
Volume46
Issue number3
StatePublished - Jan 1 2016

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Gastroenterology
Liver Diseases
Latin America
Pediatrics
Hematologic Tests
Research
Disease Progression
Epidemiology
Fibrosis
Public Health
Obesity
Biopsy
Liver
Non-alcoholic Fatty Liver Disease

Keywords

  • Adolescentes
  • Children
  • Metabolic syndrome
  • Non alcoholic fatty liver disease
  • Non alcoholic steatohepatitis

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Enfermedad de hígado graso no alcohólico (EHGNA) : Revisión y puesta al día. Grupo de trabajo de la sociedad latinoamericana de gastroenterología hepatología y nutrición pediátrica (SLAGHNP). / Quintero, Fernando Sarmiento; Botero, Verónica; Agostino, Daniel D.; Carbajal, Laura Delgado; Olivera, María Rita Dewaele; Guzmán, Celina; Játiva, Edgar; Martin, Graciela Teresita; Castro, Milton Mejía; Paranza, Lourdes Ortiz; Uego, María Cecilia Pabón; Quintana, Luis Peña; Quiros, Ruben; Rodríguez, Nelson Ramírez; Ramonet, Margarita; Medina, Juan Rivera; Sanabria, Marta; Sánchez Franco, Claudia P.; Valdiviezo, Lidia Patricia; Galoppo, Cristina.

In: Acta Gastroenterologica Latinoamericana, Vol. 46, No. 3, 01.01.2016, p. 246-264.

Research output: Contribution to journalReview article

Quintero, FS, Botero, V, Agostino, DD, Carbajal, LD, Olivera, MRD, Guzmán, C, Játiva, E, Martin, GT, Castro, MM, Paranza, LO, Uego, MCP, Quintana, LP, Quiros, R, Rodríguez, NR, Ramonet, M, Medina, JR, Sanabria, M, Sánchez Franco, CP, Valdiviezo, LP & Galoppo, C 2016, 'Enfermedad de hígado graso no alcohólico (EHGNA): Revisión y puesta al día. Grupo de trabajo de la sociedad latinoamericana de gastroenterología hepatología y nutrición pediátrica (SLAGHNP)', Acta Gastroenterologica Latinoamericana, vol. 46, no. 3, pp. 246-264.
Quintero, Fernando Sarmiento ; Botero, Verónica ; Agostino, Daniel D. ; Carbajal, Laura Delgado ; Olivera, María Rita Dewaele ; Guzmán, Celina ; Játiva, Edgar ; Martin, Graciela Teresita ; Castro, Milton Mejía ; Paranza, Lourdes Ortiz ; Uego, María Cecilia Pabón ; Quintana, Luis Peña ; Quiros, Ruben ; Rodríguez, Nelson Ramírez ; Ramonet, Margarita ; Medina, Juan Rivera ; Sanabria, Marta ; Sánchez Franco, Claudia P. ; Valdiviezo, Lidia Patricia ; Galoppo, Cristina. / Enfermedad de hígado graso no alcohólico (EHGNA) : Revisión y puesta al día. Grupo de trabajo de la sociedad latinoamericana de gastroenterología hepatología y nutrición pediátrica (SLAGHNP). In: Acta Gastroenterologica Latinoamericana. 2016 ; Vol. 46, No. 3. pp. 246-264.
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abstract = "Summary Along with obesity, non-alcoholic fatty liver disease, and its progression to esteatohepatitis, have become the most frequent liver disease among children and teenagers. Since cirrhosis could be an outcome of this condition, it is urgent to test for it in overweight and obese patients. Objectives. To compile in a single article strategies for clinical coaching and handling of children with this condition. On the basis of this revision, to promote research projects. Methods. SLAGHNP/LAPSGHAN, under responsibility and supervision of an editor/coordinator who chose contents and references with the best evidence, called its associates to perform this revision, after which edition and unification of the contents proposed. Results. The severity of EHGNA/ EHNA is established as a new infant liver disease and the lack of information on it in Latin America is noted unlike the United State, where its status as the most prevalent hepatopathy among children has been already established. Usefulness of blood chemistry tests and images is emphasized; although it has not been established when it should be recommended, it is clear liver biopsy is the gold standard for detecting the disease. Conclusions. It is important to start in Latin America research and follow-up programs on this disease, whose rapid progression will be continentwise a public health concern in the near future. A latin american register should be started under leadership of SLAGHNP/LAPSGHAN to establish this liver disease's epidemiology, establish a clinical diagnosis and choose adequate complimentary tests to confirm diagnosis.",
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T1 - Enfermedad de hígado graso no alcohólico (EHGNA)

T2 - Revisión y puesta al día. Grupo de trabajo de la sociedad latinoamericana de gastroenterología hepatología y nutrición pediátrica (SLAGHNP)

AU - Quintero, Fernando Sarmiento

AU - Botero, Verónica

AU - Agostino, Daniel D.

AU - Carbajal, Laura Delgado

AU - Olivera, María Rita Dewaele

AU - Guzmán, Celina

AU - Játiva, Edgar

AU - Martin, Graciela Teresita

AU - Castro, Milton Mejía

AU - Paranza, Lourdes Ortiz

AU - Uego, María Cecilia Pabón

AU - Quintana, Luis Peña

AU - Quiros, Ruben

AU - Rodríguez, Nelson Ramírez

AU - Ramonet, Margarita

AU - Medina, Juan Rivera

AU - Sanabria, Marta

AU - Sánchez Franco, Claudia P.

AU - Valdiviezo, Lidia Patricia

AU - Galoppo, Cristina

PY - 2016/1/1

Y1 - 2016/1/1

N2 - Summary Along with obesity, non-alcoholic fatty liver disease, and its progression to esteatohepatitis, have become the most frequent liver disease among children and teenagers. Since cirrhosis could be an outcome of this condition, it is urgent to test for it in overweight and obese patients. Objectives. To compile in a single article strategies for clinical coaching and handling of children with this condition. On the basis of this revision, to promote research projects. Methods. SLAGHNP/LAPSGHAN, under responsibility and supervision of an editor/coordinator who chose contents and references with the best evidence, called its associates to perform this revision, after which edition and unification of the contents proposed. Results. The severity of EHGNA/ EHNA is established as a new infant liver disease and the lack of information on it in Latin America is noted unlike the United State, where its status as the most prevalent hepatopathy among children has been already established. Usefulness of blood chemistry tests and images is emphasized; although it has not been established when it should be recommended, it is clear liver biopsy is the gold standard for detecting the disease. Conclusions. It is important to start in Latin America research and follow-up programs on this disease, whose rapid progression will be continentwise a public health concern in the near future. A latin american register should be started under leadership of SLAGHNP/LAPSGHAN to establish this liver disease's epidemiology, establish a clinical diagnosis and choose adequate complimentary tests to confirm diagnosis.

AB - Summary Along with obesity, non-alcoholic fatty liver disease, and its progression to esteatohepatitis, have become the most frequent liver disease among children and teenagers. Since cirrhosis could be an outcome of this condition, it is urgent to test for it in overweight and obese patients. Objectives. To compile in a single article strategies for clinical coaching and handling of children with this condition. On the basis of this revision, to promote research projects. Methods. SLAGHNP/LAPSGHAN, under responsibility and supervision of an editor/coordinator who chose contents and references with the best evidence, called its associates to perform this revision, after which edition and unification of the contents proposed. Results. The severity of EHGNA/ EHNA is established as a new infant liver disease and the lack of information on it in Latin America is noted unlike the United State, where its status as the most prevalent hepatopathy among children has been already established. Usefulness of blood chemistry tests and images is emphasized; although it has not been established when it should be recommended, it is clear liver biopsy is the gold standard for detecting the disease. Conclusions. It is important to start in Latin America research and follow-up programs on this disease, whose rapid progression will be continentwise a public health concern in the near future. A latin american register should be started under leadership of SLAGHNP/LAPSGHAN to establish this liver disease's epidemiology, establish a clinical diagnosis and choose adequate complimentary tests to confirm diagnosis.

KW - Adolescentes

KW - Children

KW - Metabolic syndrome

KW - Non alcoholic fatty liver disease

KW - Non alcoholic steatohepatitis

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