Enfermedad de hígado graso no alcohólico (EHGNA): Revisión y puesta al día. Grupo de trabajo de la sociedad latinoamericana de gastroenterología hepatología y nutrición pediátrica (SLAGHNP)

Translated title of the contribution: Non-alcoholic fatty liver disease (NAFLD): Review and update. Working group of the latinamerican society of pediatric gastroenterology, hepatology and nutrition (LASPGHAN)

Fernando Sarmiento Quintero, Verónica Botero, Daniel D. Agostino, Laura Delgado Carbajal, María Rita Dewaele Olivera, Celina Guzmán, Edgar Játiva, Graciela Teresita Martin, Milton Mejía Castro, Lourdes Ortiz Paranza, María Cecilia Pabón Uego, Luis Peña Quintana, Ruben Quiros, Nelson Ramírez Rodríguez, Margarita Ramonet, Juan Rivera Medina, Marta Sanabria, Claudia P. Sánchez Franco, Lidia Patricia Valdiviezo, Cristina Galoppo

Research output: Contribution to journalReview article

Abstract

Summary Along with obesity, non-alcoholic fatty liver disease, and its progression to esteatohepatitis, have become the most frequent liver disease among children and teenagers. Since cirrhosis could be an outcome of this condition, it is urgent to test for it in overweight and obese patients. Objectives. To compile in a single article strategies for clinical coaching and handling of children with this condition. On the basis of this revision, to promote research projects. Methods. SLAGHNP/LAPSGHAN, under responsibility and supervision of an editor/coordinator who chose contents and references with the best evidence, called its associates to perform this revision, after which edition and unification of the contents proposed. Results. The severity of EHGNA/ EHNA is established as a new infant liver disease and the lack of information on it in Latin America is noted unlike the United State, where its status as the most prevalent hepatopathy among children has been already established. Usefulness of blood chemistry tests and images is emphasized; although it has not been established when it should be recommended, it is clear liver biopsy is the gold standard for detecting the disease. Conclusions. It is important to start in Latin America research and follow-up programs on this disease, whose rapid progression will be continentwise a public health concern in the near future. A latin american register should be started under leadership of SLAGHNP/LAPSGHAN to establish this liver disease's epidemiology, establish a clinical diagnosis and choose adequate complimentary tests to confirm diagnosis.

Original languageSpanish
Pages (from-to)246-264
Number of pages19
JournalActa Gastroenterologica Latinoamericana
Volume46
Issue number3
Publication statusPublished - Jan 1 2016

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Keywords

  • Adolescentes
  • Children
  • Metabolic syndrome
  • Non alcoholic fatty liver disease
  • Non alcoholic steatohepatitis

ASJC Scopus subject areas

  • Gastroenterology

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