Nomograms for two-dimensional echocardiography derived valvular and arterial dimensions in Caucasian children

Massimiliano Cantinotti, Raffaele Giordano, Marco Scalese, Bruno Murzi, Nadia Assanta, Isabella Spadoni, Crocetti Maura, Marotta Marco, Sabrina Molinaro, Shelby Kutty, Giorgio Iervasi

Research output: Contribution to journalArticle

13 Scopus citations

Abstract

Background Despite recent advances, current pediatric echocardiographic nomograms for valvular and arterial dimensions remain limited. Methods We prospectively studied healthy Caucasian Italian children by two-dimensional (2D) echocardiography. Echocardiographic measurements for 18 valvular and arterial dimensions were performed and models were generated testing for linear, logarithmic, exponential, and square root relationships. Heteroscedasticity was accounted for by White or Breusch–Pagan test. Age, weight, height, heart rate, and body surface area (BSA) were used as independent variables in different analyses to predict the mean values of each measurement. Structured Z-scores were then computed. Results In all, 1151 subjects (age 0 days to 17 years; 45% females; BSA 0.12–2.12 m2) were studied. The Haycock formula was used when presenting data as predicted values (mean ± 2 SDs) for a given BSA and within equations relating echocardiographic measurements to BSA. The predicted values and Z-score boundaries for all measurements are presented. Conclusions We report echocardiographic nomograms for valvular and arterial dimensions derived from a large population of children. Integration of these data with those of previous reports would allow for a comprehensive coverage of pediatric 2D echocardiographic nomograms for measurement of 2D cardiac structures.

Original languageEnglish (US)
Pages (from-to)208-215
Number of pages8
JournalJournal of Cardiology
Volume69
Issue number1
DOIs
StatePublished - Jan 1 2017

    Fingerprint

Keywords

  • Children
  • Echocardiography
  • Nomograms

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Cantinotti, M., Giordano, R., Scalese, M., Murzi, B., Assanta, N., Spadoni, I., Maura, C., Marco, M., Molinaro, S., Kutty, S., & Iervasi, G. (2017). Nomograms for two-dimensional echocardiography derived valvular and arterial dimensions in Caucasian children. Journal of Cardiology, 69(1), 208-215. https://doi.org/10.1016/j.jjcc.2016.03.010