Nicotinic acid supplementation in the context of alcoholic liver injury: Friend or foe?

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Li and colleagues (2014) in this issue report that dietary nicotinic acid (NA) supplementation ameliorates ethanol-induced hepatic steatosis, but a deficiency does not worsen injury induced by alcohol alone. The authors further present some mechanistic insights into the protective role of NA supplementation. Results of this and other previous studies in the context of alcoholic liver injury raise one important question as to what should be an adequate dose of NA that will provide the maximum benefit to hepatic and extrahepatic tissues and with minimum adverse effects.

Original languageEnglish (US)
Pages (from-to)1829-1831
Number of pages3
JournalAlcoholism: Clinical and Experimental Research
Issue number7
StatePublished - Jul 2014



  • Ethanol
  • Hepatic
  • Methylation potential
  • Niacin
  • Prevention

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Toxicology
  • Psychiatry and Mental health

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