NEW ENZYME IMMUNOASSAYS FOR MEASUREMENT OF INFLUENZA A/VICTORIA/3/75 VIRUS IN NASAL WASHES

Richard A. Berg, Stephen I. Rennard, Brian R. Murphy, Robert H. Yolken, Raphael Dolin, Stephen E. Straus

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27 Scopus citations

Abstract

Nasopharyngeal (NP) washes from 12 patients experimentally infected with influenza A/Victoria/3/75 wild-type virus were tested in 2 newly developed enzyme-immunoassay (EIA) systems. Results were compared with infectivity titres of the NP wash specimens in rhesus monkey kidney-tissue culture. EIA detected A/Victoria/3/75 hæmagglutinin antigen for more days than did culture. EIA is also rapid and easy to do in large numbers; hence it may have advantages over culture methods for the diagnosis of influenza infections and the investigation of influenza epidemiology.

Original languageEnglish (US)
Pages (from-to)851-853
Number of pages3
JournalThe Lancet
Volume315
Issue number8173
DOIs
Publication statusPublished - Apr 19 1980

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ASJC Scopus subject areas

  • Medicine(all)

Cite this

Berg, R. A., Rennard, S. I., Murphy, B. R., Yolken, R. H., Dolin, R., & Straus, S. E. (1980). NEW ENZYME IMMUNOASSAYS FOR MEASUREMENT OF INFLUENZA A/VICTORIA/3/75 VIRUS IN NASAL WASHES. The Lancet, 315(8173), 851-853. https://doi.org/10.1016/S0140-6736(80)91356-2