NEW ENZYME IMMUNOASSAYS FOR MEASUREMENT OF INFLUENZA A/VICTORIA/3/75 VIRUS IN NASAL WASHES

Richard A. Berg, Stephen I. Rennard, Brian R. Murphy, Robert H. Yolken, Raphael Dolin, Stephen E. Straus

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

Nasopharyngeal (NP) washes from 12 patients experimentally infected with influenza A/Victoria/3/75 wild-type virus were tested in 2 newly developed enzyme-immunoassay (EIA) systems. Results were compared with infectivity titres of the NP wash specimens in rhesus monkey kidney-tissue culture. EIA detected A/Victoria/3/75 hæmagglutinin antigen for more days than did culture. EIA is also rapid and easy to do in large numbers; hence it may have advantages over culture methods for the diagnosis of influenza infections and the investigation of influenza epidemiology.

Original languageEnglish (US)
Pages (from-to)851-853
Number of pages3
JournalThe Lancet
Volume315
Issue number8173
DOIs
StatePublished - Apr 19 1980

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Immunoenzyme Techniques
Nose
Human Influenza
Victoria
Viruses
Macaca mulatta
Epidemiology
Kidney
Antigens
Infection

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Berg, R. A., Rennard, S. I., Murphy, B. R., Yolken, R. H., Dolin, R., & Straus, S. E. (1980). NEW ENZYME IMMUNOASSAYS FOR MEASUREMENT OF INFLUENZA A/VICTORIA/3/75 VIRUS IN NASAL WASHES. The Lancet, 315(8173), 851-853. https://doi.org/10.1016/S0140-6736(80)91356-2

NEW ENZYME IMMUNOASSAYS FOR MEASUREMENT OF INFLUENZA A/VICTORIA/3/75 VIRUS IN NASAL WASHES. / Berg, Richard A.; Rennard, Stephen I.; Murphy, Brian R.; Yolken, Robert H.; Dolin, Raphael; Straus, Stephen E.

In: The Lancet, Vol. 315, No. 8173, 19.04.1980, p. 851-853.

Research output: Contribution to journalArticle

Berg, RA, Rennard, SI, Murphy, BR, Yolken, RH, Dolin, R & Straus, SE 1980, 'NEW ENZYME IMMUNOASSAYS FOR MEASUREMENT OF INFLUENZA A/VICTORIA/3/75 VIRUS IN NASAL WASHES', The Lancet, vol. 315, no. 8173, pp. 851-853. https://doi.org/10.1016/S0140-6736(80)91356-2
Berg RA, Rennard SI, Murphy BR, Yolken RH, Dolin R, Straus SE. NEW ENZYME IMMUNOASSAYS FOR MEASUREMENT OF INFLUENZA A/VICTORIA/3/75 VIRUS IN NASAL WASHES. The Lancet. 1980 Apr 19;315(8173):851-853. https://doi.org/10.1016/S0140-6736(80)91356-2
Berg, Richard A. ; Rennard, Stephen I. ; Murphy, Brian R. ; Yolken, Robert H. ; Dolin, Raphael ; Straus, Stephen E. / NEW ENZYME IMMUNOASSAYS FOR MEASUREMENT OF INFLUENZA A/VICTORIA/3/75 VIRUS IN NASAL WASHES. In: The Lancet. 1980 ; Vol. 315, No. 8173. pp. 851-853.
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