Neuro-Ophthalmic Presentation of Neuro-Sweet Disease

Padmaja Sudhakar, Stuart Tobin, William O Connor, Sachin Kedar

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Acute febrile neutrophilic dermatosis (Sweet syndrome) is a systemic inflammatory condition usually associated with autoimmune or neoplastic processes and characterised by inflammatory dermatologic lesions such as erythematous plaques and papules associated with fever and leukocytosis. Neurological and ophthalmological involvement is rare. The authors describe an unusual case of Sweet syndrome associated with microscopic polyangiitis presenting with papilloedema, anterior uveitis, and skin rash. Years later, he developed acute posterior multifocal placoid pigment epitheliopathy. Treatment with immunosuppressive medications led to a relapsing remitting course with maximum benefit from use of steroids. The authors describe the difficulties in diagnosis and treatment of this rare case.

Original languageEnglish (US)
Pages (from-to)202-206
Number of pages5
JournalNeuro-Ophthalmology
Volume41
Issue number4
DOIs
StatePublished - Jul 4 2017

Fingerprint

Sweet Syndrome
Microscopic Polyangiitis
Anterior Uveitis
Neoplastic Processes
Papilledema
Leukocytosis
Immunosuppressive Agents
Exanthema
Fever
Steroids

Keywords

  • APMPPE
  • Sweet syndrome
  • microscopic polyangiitis
  • neuro-Sweet
  • papilloedema

ASJC Scopus subject areas

  • Ophthalmology
  • Clinical Neurology

Cite this

Neuro-Ophthalmic Presentation of Neuro-Sweet Disease. / Sudhakar, Padmaja; Tobin, Stuart; O Connor, William; Kedar, Sachin.

In: Neuro-Ophthalmology, Vol. 41, No. 4, 04.07.2017, p. 202-206.

Research output: Contribution to journalArticle

Sudhakar, Padmaja ; Tobin, Stuart ; O Connor, William ; Kedar, Sachin. / Neuro-Ophthalmic Presentation of Neuro-Sweet Disease. In: Neuro-Ophthalmology. 2017 ; Vol. 41, No. 4. pp. 202-206.
@article{4553446cd3ea4ad08e5917bc3918112d,
title = "Neuro-Ophthalmic Presentation of Neuro-Sweet Disease",
abstract = "Acute febrile neutrophilic dermatosis (Sweet syndrome) is a systemic inflammatory condition usually associated with autoimmune or neoplastic processes and characterised by inflammatory dermatologic lesions such as erythematous plaques and papules associated with fever and leukocytosis. Neurological and ophthalmological involvement is rare. The authors describe an unusual case of Sweet syndrome associated with microscopic polyangiitis presenting with papilloedema, anterior uveitis, and skin rash. Years later, he developed acute posterior multifocal placoid pigment epitheliopathy. Treatment with immunosuppressive medications led to a relapsing remitting course with maximum benefit from use of steroids. The authors describe the difficulties in diagnosis and treatment of this rare case.",
keywords = "APMPPE, Sweet syndrome, microscopic polyangiitis, neuro-Sweet, papilloedema",
author = "Padmaja Sudhakar and Stuart Tobin and {O Connor}, William and Sachin Kedar",
year = "2017",
month = "7",
day = "4",
doi = "10.1080/01658107.2017.1291687",
language = "English (US)",
volume = "41",
pages = "202--206",
journal = "Neuro-Ophthalmology",
issn = "0165-8107",
publisher = "Informa Healthcare",
number = "4",

}

TY - JOUR

T1 - Neuro-Ophthalmic Presentation of Neuro-Sweet Disease

AU - Sudhakar, Padmaja

AU - Tobin, Stuart

AU - O Connor, William

AU - Kedar, Sachin

PY - 2017/7/4

Y1 - 2017/7/4

N2 - Acute febrile neutrophilic dermatosis (Sweet syndrome) is a systemic inflammatory condition usually associated with autoimmune or neoplastic processes and characterised by inflammatory dermatologic lesions such as erythematous plaques and papules associated with fever and leukocytosis. Neurological and ophthalmological involvement is rare. The authors describe an unusual case of Sweet syndrome associated with microscopic polyangiitis presenting with papilloedema, anterior uveitis, and skin rash. Years later, he developed acute posterior multifocal placoid pigment epitheliopathy. Treatment with immunosuppressive medications led to a relapsing remitting course with maximum benefit from use of steroids. The authors describe the difficulties in diagnosis and treatment of this rare case.

AB - Acute febrile neutrophilic dermatosis (Sweet syndrome) is a systemic inflammatory condition usually associated with autoimmune or neoplastic processes and characterised by inflammatory dermatologic lesions such as erythematous plaques and papules associated with fever and leukocytosis. Neurological and ophthalmological involvement is rare. The authors describe an unusual case of Sweet syndrome associated with microscopic polyangiitis presenting with papilloedema, anterior uveitis, and skin rash. Years later, he developed acute posterior multifocal placoid pigment epitheliopathy. Treatment with immunosuppressive medications led to a relapsing remitting course with maximum benefit from use of steroids. The authors describe the difficulties in diagnosis and treatment of this rare case.

KW - APMPPE

KW - Sweet syndrome

KW - microscopic polyangiitis

KW - neuro-Sweet

KW - papilloedema

UR - http://www.scopus.com/inward/record.url?scp=85015191893&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85015191893&partnerID=8YFLogxK

U2 - 10.1080/01658107.2017.1291687

DO - 10.1080/01658107.2017.1291687

M3 - Article

C2 - 29344060

AN - SCOPUS:85015191893

VL - 41

SP - 202

EP - 206

JO - Neuro-Ophthalmology

JF - Neuro-Ophthalmology

SN - 0165-8107

IS - 4

ER -