Neural mechanisms underlying food motivation in children and adolescents

Laura M. Holsen, Jennifer R. Zarcone, Travis I. Thompson, William M. Brooks, Mary F. Anderson, Jasjit S. Ahluwalia, Nicole L. Nollen, Cary R. Savage

Research output: Contribution to journalArticle

104 Citations (Scopus)

Abstract

Dramatic increases in childhood obesity necessitate a more complete understanding of neural mechanisms of hunger and satiation in pediatric populations. In this study, normal weight children and adolescents underwent functional magnetic resonance imaging (fMRI) scanning before and after eating a meal. Participants showed increased activation to visual food stimuli in the amygdala, medial frontal/orbitofrontal cortex, and insula in the pre-meal condition; no regions of interest responded in the post-meal condition. These results closely parallel previous findings in adults. In addition, we found evidence for habituation to food stimuli in the amygdala within the pre-meal session. These findings provide evidence that normal patterns of neural activity related to food motivation begin in childhood. Results have implications for obese children and adults, who may have abnormal hunger and satiation mechanisms.

Original languageEnglish (US)
Pages (from-to)669-676
Number of pages8
JournalNeuroImage
Volume27
Issue number3
DOIs
StatePublished - Sep 1 2005

Fingerprint

Meals
Motivation
Satiation
Food
Hunger
Amygdala
Pediatric Obesity
Frontal Lobe
Prefrontal Cortex
Eating
Magnetic Resonance Imaging
Pediatrics
Weights and Measures
Population

Keywords

  • Amygdala
  • Food motivation
  • Obesity
  • Pediatric
  • fMRI

ASJC Scopus subject areas

  • Neurology
  • Cognitive Neuroscience

Cite this

Holsen, L. M., Zarcone, J. R., Thompson, T. I., Brooks, W. M., Anderson, M. F., Ahluwalia, J. S., ... Savage, C. R. (2005). Neural mechanisms underlying food motivation in children and adolescents. NeuroImage, 27(3), 669-676. https://doi.org/10.1016/j.neuroimage.2005.04.043

Neural mechanisms underlying food motivation in children and adolescents. / Holsen, Laura M.; Zarcone, Jennifer R.; Thompson, Travis I.; Brooks, William M.; Anderson, Mary F.; Ahluwalia, Jasjit S.; Nollen, Nicole L.; Savage, Cary R.

In: NeuroImage, Vol. 27, No. 3, 01.09.2005, p. 669-676.

Research output: Contribution to journalArticle

Holsen, LM, Zarcone, JR, Thompson, TI, Brooks, WM, Anderson, MF, Ahluwalia, JS, Nollen, NL & Savage, CR 2005, 'Neural mechanisms underlying food motivation in children and adolescents', NeuroImage, vol. 27, no. 3, pp. 669-676. https://doi.org/10.1016/j.neuroimage.2005.04.043
Holsen LM, Zarcone JR, Thompson TI, Brooks WM, Anderson MF, Ahluwalia JS et al. Neural mechanisms underlying food motivation in children and adolescents. NeuroImage. 2005 Sep 1;27(3):669-676. https://doi.org/10.1016/j.neuroimage.2005.04.043
Holsen, Laura M. ; Zarcone, Jennifer R. ; Thompson, Travis I. ; Brooks, William M. ; Anderson, Mary F. ; Ahluwalia, Jasjit S. ; Nollen, Nicole L. ; Savage, Cary R. / Neural mechanisms underlying food motivation in children and adolescents. In: NeuroImage. 2005 ; Vol. 27, No. 3. pp. 669-676.
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