Neural invasion in the staging of pancreatic cancer

Parviz M. Pour, Richard H. Bell, Surinder Kumar Batra

Research output: Contribution to journalArticle

78 Citations (Scopus)

Abstract

The natural history of pancreatic ductal adenocarcinoma makes it one of the most malignant human diseases. Unknown etiology, lack of early symptoms, explosive outcome, short survival, and resistance to therapy are hallmarks of this cancer. Although surgery has been shown to be an effective therapeutic approach, the inevitable tendency for recurrence, even after apparently curative operation, has remained a mystery. Ironically, the reasons for this recurrence, which usually leads to the death of the patient within 1 or 2 years after surgery, have not been a focus of research. Several studies highlighting this problem and the possible explanations have been performed by Japanese investigators.

Original languageEnglish (US)
Pages (from-to)322-325
Number of pages4
JournalPancreas
Volume26
Issue number4
DOIs
StatePublished - May 1 2003

Fingerprint

Pancreatic Neoplasms
Recurrence
Adenocarcinoma
Research Personnel
Survival
Therapeutics
Research
Neoplasms

Keywords

  • Locoregional recurrence
  • Neural invasion
  • Pancreatic cancer

ASJC Scopus subject areas

  • Gastroenterology
  • Endocrinology

Cite this

Neural invasion in the staging of pancreatic cancer. / Pour, Parviz M.; Bell, Richard H.; Batra, Surinder Kumar.

In: Pancreas, Vol. 26, No. 4, 01.05.2003, p. 322-325.

Research output: Contribution to journalArticle

Pour, Parviz M. ; Bell, Richard H. ; Batra, Surinder Kumar. / Neural invasion in the staging of pancreatic cancer. In: Pancreas. 2003 ; Vol. 26, No. 4. pp. 322-325.
@article{6d91eb5227104d3cba47219d436fc685,
title = "Neural invasion in the staging of pancreatic cancer",
abstract = "The natural history of pancreatic ductal adenocarcinoma makes it one of the most malignant human diseases. Unknown etiology, lack of early symptoms, explosive outcome, short survival, and resistance to therapy are hallmarks of this cancer. Although surgery has been shown to be an effective therapeutic approach, the inevitable tendency for recurrence, even after apparently curative operation, has remained a mystery. Ironically, the reasons for this recurrence, which usually leads to the death of the patient within 1 or 2 years after surgery, have not been a focus of research. Several studies highlighting this problem and the possible explanations have been performed by Japanese investigators.",
keywords = "Locoregional recurrence, Neural invasion, Pancreatic cancer",
author = "Pour, {Parviz M.} and Bell, {Richard H.} and Batra, {Surinder Kumar}",
year = "2003",
month = "5",
day = "1",
doi = "10.1097/00006676-200305000-00002",
language = "English (US)",
volume = "26",
pages = "322--325",
journal = "Pancreas",
issn = "0885-3177",
publisher = "Lippincott Williams and Wilkins",
number = "4",

}

TY - JOUR

T1 - Neural invasion in the staging of pancreatic cancer

AU - Pour, Parviz M.

AU - Bell, Richard H.

AU - Batra, Surinder Kumar

PY - 2003/5/1

Y1 - 2003/5/1

N2 - The natural history of pancreatic ductal adenocarcinoma makes it one of the most malignant human diseases. Unknown etiology, lack of early symptoms, explosive outcome, short survival, and resistance to therapy are hallmarks of this cancer. Although surgery has been shown to be an effective therapeutic approach, the inevitable tendency for recurrence, even after apparently curative operation, has remained a mystery. Ironically, the reasons for this recurrence, which usually leads to the death of the patient within 1 or 2 years after surgery, have not been a focus of research. Several studies highlighting this problem and the possible explanations have been performed by Japanese investigators.

AB - The natural history of pancreatic ductal adenocarcinoma makes it one of the most malignant human diseases. Unknown etiology, lack of early symptoms, explosive outcome, short survival, and resistance to therapy are hallmarks of this cancer. Although surgery has been shown to be an effective therapeutic approach, the inevitable tendency for recurrence, even after apparently curative operation, has remained a mystery. Ironically, the reasons for this recurrence, which usually leads to the death of the patient within 1 or 2 years after surgery, have not been a focus of research. Several studies highlighting this problem and the possible explanations have been performed by Japanese investigators.

KW - Locoregional recurrence

KW - Neural invasion

KW - Pancreatic cancer

UR - http://www.scopus.com/inward/record.url?scp=0038068132&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0038068132&partnerID=8YFLogxK

U2 - 10.1097/00006676-200305000-00002

DO - 10.1097/00006676-200305000-00002

M3 - Article

VL - 26

SP - 322

EP - 325

JO - Pancreas

JF - Pancreas

SN - 0885-3177

IS - 4

ER -