Neural activation within the prefrontal cortices during the goal-directed motor actions of children with hemiplegic cerebral palsy

Swati M. Surkar, Rashelle M. Hoffman, Regina Harbourne, Max J. Kurz

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

The primary aim of the study was to explore the prefrontal cortical (PFC) activation while performing a shape-matching motor task in children with hemiplegic cerebral palsy (HCP) as compared with typically developing (TD) children. Fifteen TD children (age = 5.9 × 1.1 years) and 12 children with HCP (age = 6.8 × 2.9 years) were included. We assessed the PFC activation while performing an ecologically valid upper extremity shape-matching task of different complexities by measuring the concentration of oxygenated hemoglobin (HbO) using functional near-infrared spectroscopy. The motor task performance was assessed by quantifying the average number of shapes matched, reaction time (RT), task errors, nine-hole peg test (NHPT), and the box and block test (BBT). Overall, there was a systematic increase in the HbO in the PFC across the shape-matching complexity conditions. Our results also revealed that the children with HCP had an increased amount of PFC activation while performing all of the shape-matching tasks. The increased PFC activation paralleled the differences in the number of shapes matched, RT, task errors, NHPT, and BBT. The atypical motor actions seen in children with HCP may be partially related to the greater cognitive demands placed on the PFC.

Original languageEnglish (US)
Article number011021
JournalNeurophotonics
Volume5
Issue number1
DOIs
StatePublished - Jan 1 2018

Fingerprint

Cerebral Palsy
Prefrontal Cortex
Reaction Time
Near-Infrared Spectroscopy
Task Performance and Analysis
Upper Extremity
Hemoglobins

Keywords

  • Action planning
  • Cognition
  • Motor performance
  • Movement dysfunction

ASJC Scopus subject areas

  • Neuroscience (miscellaneous)
  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging

Cite this

Neural activation within the prefrontal cortices during the goal-directed motor actions of children with hemiplegic cerebral palsy. / Surkar, Swati M.; Hoffman, Rashelle M.; Harbourne, Regina; Kurz, Max J.

In: Neurophotonics, Vol. 5, No. 1, 011021, 01.01.2018.

Research output: Contribution to journalArticle

@article{3c9be6038e0645a8929cf9e9ed5f03d1,
title = "Neural activation within the prefrontal cortices during the goal-directed motor actions of children with hemiplegic cerebral palsy",
abstract = "The primary aim of the study was to explore the prefrontal cortical (PFC) activation while performing a shape-matching motor task in children with hemiplegic cerebral palsy (HCP) as compared with typically developing (TD) children. Fifteen TD children (age = 5.9 × 1.1 years) and 12 children with HCP (age = 6.8 × 2.9 years) were included. We assessed the PFC activation while performing an ecologically valid upper extremity shape-matching task of different complexities by measuring the concentration of oxygenated hemoglobin (HbO) using functional near-infrared spectroscopy. The motor task performance was assessed by quantifying the average number of shapes matched, reaction time (RT), task errors, nine-hole peg test (NHPT), and the box and block test (BBT). Overall, there was a systematic increase in the HbO in the PFC across the shape-matching complexity conditions. Our results also revealed that the children with HCP had an increased amount of PFC activation while performing all of the shape-matching tasks. The increased PFC activation paralleled the differences in the number of shapes matched, RT, task errors, NHPT, and BBT. The atypical motor actions seen in children with HCP may be partially related to the greater cognitive demands placed on the PFC.",
keywords = "Action planning, Cognition, Motor performance, Movement dysfunction",
author = "Surkar, {Swati M.} and Hoffman, {Rashelle M.} and Regina Harbourne and Kurz, {Max J.}",
year = "2018",
month = "1",
day = "1",
doi = "10.1117/1.NPh.5.1.011021",
language = "English (US)",
volume = "5",
journal = "Neurophotonics",
issn = "2329-4248",
publisher = "SPIE",
number = "1",

}

TY - JOUR

T1 - Neural activation within the prefrontal cortices during the goal-directed motor actions of children with hemiplegic cerebral palsy

AU - Surkar, Swati M.

AU - Hoffman, Rashelle M.

AU - Harbourne, Regina

AU - Kurz, Max J.

PY - 2018/1/1

Y1 - 2018/1/1

N2 - The primary aim of the study was to explore the prefrontal cortical (PFC) activation while performing a shape-matching motor task in children with hemiplegic cerebral palsy (HCP) as compared with typically developing (TD) children. Fifteen TD children (age = 5.9 × 1.1 years) and 12 children with HCP (age = 6.8 × 2.9 years) were included. We assessed the PFC activation while performing an ecologically valid upper extremity shape-matching task of different complexities by measuring the concentration of oxygenated hemoglobin (HbO) using functional near-infrared spectroscopy. The motor task performance was assessed by quantifying the average number of shapes matched, reaction time (RT), task errors, nine-hole peg test (NHPT), and the box and block test (BBT). Overall, there was a systematic increase in the HbO in the PFC across the shape-matching complexity conditions. Our results also revealed that the children with HCP had an increased amount of PFC activation while performing all of the shape-matching tasks. The increased PFC activation paralleled the differences in the number of shapes matched, RT, task errors, NHPT, and BBT. The atypical motor actions seen in children with HCP may be partially related to the greater cognitive demands placed on the PFC.

AB - The primary aim of the study was to explore the prefrontal cortical (PFC) activation while performing a shape-matching motor task in children with hemiplegic cerebral palsy (HCP) as compared with typically developing (TD) children. Fifteen TD children (age = 5.9 × 1.1 years) and 12 children with HCP (age = 6.8 × 2.9 years) were included. We assessed the PFC activation while performing an ecologically valid upper extremity shape-matching task of different complexities by measuring the concentration of oxygenated hemoglobin (HbO) using functional near-infrared spectroscopy. The motor task performance was assessed by quantifying the average number of shapes matched, reaction time (RT), task errors, nine-hole peg test (NHPT), and the box and block test (BBT). Overall, there was a systematic increase in the HbO in the PFC across the shape-matching complexity conditions. Our results also revealed that the children with HCP had an increased amount of PFC activation while performing all of the shape-matching tasks. The increased PFC activation paralleled the differences in the number of shapes matched, RT, task errors, NHPT, and BBT. The atypical motor actions seen in children with HCP may be partially related to the greater cognitive demands placed on the PFC.

KW - Action planning

KW - Cognition

KW - Motor performance

KW - Movement dysfunction

UR - http://www.scopus.com/inward/record.url?scp=85044069080&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85044069080&partnerID=8YFLogxK

U2 - 10.1117/1.NPh.5.1.011021

DO - 10.1117/1.NPh.5.1.011021

M3 - Article

C2 - 29541647

AN - SCOPUS:85044069080

VL - 5

JO - Neurophotonics

JF - Neurophotonics

SN - 2329-4248

IS - 1

M1 - 011021

ER -