Abstract

The authors describe a case of myeloid sarcoma of the orbit in a pediatric patient. An 8-month-old male infant presented to the ophthalmology clinic with a left orbital mass, which had been increasing in size over the previous 2 months. The mass was initially diagnosed at another clinic as an infantile hemangioma, and had been treated with a topical formulation of timolol. In the ophthalmology clinic, orbital magnetic resonance imaging showed a solid enhancing mass. A biopsy was performed, and histopathology revealed myeloid sarcoma. The disease responded well to a standard chemotherapy regimen. Myeloid sarcoma is a rare, extra-medullary presentation that can occur as an isolated tumor, concurrently with or at relapse of acute myeloid leukemia. Because few cases of myeloid sarcoma in the orbit have been reported, this case report aids in the management of myeloid sarcoma in pediatric patients. The report describes an 8-month-old male infant, the youngest patient to develop myeloid sarcoma without preexisting acute myeloid leukemia. [J Pediatr Ophthalmol Strabismus. 2016;53:e64-e68.].

Original languageEnglish (US)
Pages (from-to)e64-e68
JournalJournal of pediatric ophthalmology and strabismus
Volume53
DOIs
StatePublished - Dec 8 2016

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Myeloid Sarcoma
Orbit
Ophthalmology
Acute Myeloid Leukemia
Pediatrics
Timolol
Strabismus
Hemangioma
Magnetic Resonance Imaging
Biopsy
Recurrence
Drug Therapy

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Medicine(all)
  • Ophthalmology

Cite this

Myeloid Sarcoma in the Orbit. / Qian, Xiaoxiao; Gigantelli, James W; Abromowitch, Minnie; Morgan, Linda A.; Suh, Donny W.

In: Journal of pediatric ophthalmology and strabismus, Vol. 53, 08.12.2016, p. e64-e68.

Research output: Contribution to journalArticle

Qian, Xiaoxiao ; Gigantelli, James W ; Abromowitch, Minnie ; Morgan, Linda A. ; Suh, Donny W. / Myeloid Sarcoma in the Orbit. In: Journal of pediatric ophthalmology and strabismus. 2016 ; Vol. 53. pp. e64-e68.
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