Multiaxial mechanical behavior of the porcine anterior lens capsule

M. R. Heistand, R. M. Pedrigi, S. L. Delange, J. Dziezyc, J. D. Humphrey

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

The biomechanics of the lens capsule of the eye is important both in physiologic processes such as accommodation and clinical treatments such as cataract surgery. Although the lens capsule experiences multiaxial stresses in vivo, there have been no measurements of its multiaxial properties or possible regional heterogeneities. Rather all prior mechanical data have come from 1-D pressure-volume or uniaxial force-length tests. Here, we report a new experimental approach to study in situ the regional, multiaxial mechanical behavior of the lens capsule. Moreover, we report multiaxial data suggesting that the porcine anterior lens capsule exhibits a typical nonlinear pseudoelastic behavior over finite strains, that the in situ state is pre-stressed multiaxially, and that the meridional and circumferential directions are principal directions of strain, which is nearly equibiaxial at the pole but less so towards the equator. Such data are fundamental to much needed constitutive formulations.

Original languageEnglish (US)
Pages (from-to)168-177
Number of pages10
JournalBiomechanics and Modeling in Mechanobiology
Volume4
Issue number2-3
DOIs
StatePublished - Nov 1 2005

Fingerprint

Anterior Capsule of the Lens
Mechanical Behavior
Capsules
Lens
Lenses
Swine
Crystalline Lens
Equator
Principal direction
Biomechanical Phenomena
Cataract
Biomechanics
Finite Strain
Surgery
Pole
Pressure
Poles
Formulation
Direction compound

Keywords

  • Accommodation
  • Biomechanics
  • Cataracts
  • Stiffness
  • Stress

ASJC Scopus subject areas

  • Biotechnology
  • Modeling and Simulation
  • Mechanical Engineering

Cite this

Multiaxial mechanical behavior of the porcine anterior lens capsule. / Heistand, M. R.; Pedrigi, R. M.; Delange, S. L.; Dziezyc, J.; Humphrey, J. D.

In: Biomechanics and Modeling in Mechanobiology, Vol. 4, No. 2-3, 01.11.2005, p. 168-177.

Research output: Contribution to journalArticle

Heistand, M. R. ; Pedrigi, R. M. ; Delange, S. L. ; Dziezyc, J. ; Humphrey, J. D. / Multiaxial mechanical behavior of the porcine anterior lens capsule. In: Biomechanics and Modeling in Mechanobiology. 2005 ; Vol. 4, No. 2-3. pp. 168-177.
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