MUC1 mucin mRNA expression in cultured human nasal and bronchial epithelial cells.

Michael A Hollingsworth, Surinder Kumar Batra, W. N. Qi, J. R. Yankaskas

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

The MUC1 mucin mRNA, for which the cDNA was previously cloned from human breast and pancreatic tissues, was found to be expressed in nasal and bronchial epithelial cell primary cultures from cystic fibrotic, atopic, and normal individuals. Sequence analysis of cDNA clones from the CF/T43 cystic fibrosis nasal epithelial cell line revealed only insignificant differences in the 3' untranslated region of the mRNA when compared with the pancreas and breast mucin cDNAs.

Original languageEnglish (US)
Pages (from-to)516-520
Number of pages5
JournalAmerican journal of respiratory cell and molecular biology
Volume6
Issue number5
DOIs
StatePublished - May 1992

Fingerprint

Mucins
Nose
Complementary DNA
Epithelial Cells
Messenger RNA
Breast
3' Untranslated Regions
Cystic Fibrosis
Sequence Analysis
Pancreas
Clone Cells
Cell Culture Techniques
Tissue
Cell Line

ASJC Scopus subject areas

  • Molecular Biology
  • Pulmonary and Respiratory Medicine
  • Clinical Biochemistry
  • Cell Biology

Cite this

MUC1 mucin mRNA expression in cultured human nasal and bronchial epithelial cells. / Hollingsworth, Michael A; Batra, Surinder Kumar; Qi, W. N.; Yankaskas, J. R.

In: American journal of respiratory cell and molecular biology, Vol. 6, No. 5, 05.1992, p. 516-520.

Research output: Contribution to journalArticle

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