Monitoring the wall mechanics during stent deployment in a vessel

Brian D. Steinert, Shijia Zhao, Linxia Gu

Research output: Contribution to journalArticle

Abstract

Clinical trials have reported different restenosis rates for various stent designs 1. It is speculated that stent-induced strain concentrations on the arterial wall lead to tissue injury, which initiates restenosis 2-7. This hypothesis needs further investigations including better quantifications of non-uniform strain distribution on the artery following stent implantation. A non-contact surface strain measurement method for the stented artery is presented in this work. ARAMIS stereo optical surface strain measurement system uses two optical high speed cameras to capture the motion of each reference point, and resolve three dimensional strains over the deforming surface 8,9. As a mesh stent is deployed into a latex vessel with a random contrasting pattern sprayed or drawn on its outer surface, the surface strain is recorded at every instant of the deformation. The calculated strain distributions can then be used to understand the local lesion response, validate the computational models, and formulate hypotheses for further in vivo study.

Original languageEnglish (US)
Article numbere3945
JournalJournal of Visualized Experiments
Issue number63
DOIs
StatePublished - May 8 2012

Fingerprint

Stents
Mechanics
Monitoring
Strain measurement
Surface measurement
Arteries
Latex
High speed cameras
Latexes
Clinical Trials
Tissue
Wounds and Injuries

Keywords

  • Bioengineering
  • Biomedical engineering
  • Interaction
  • Stent
  • Stereo optical surface strain measurement system
  • Strain distribution
  • Vessel

ASJC Scopus subject areas

  • Neuroscience(all)
  • Chemical Engineering(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Immunology and Microbiology(all)

Cite this

Monitoring the wall mechanics during stent deployment in a vessel. / Steinert, Brian D.; Zhao, Shijia; Gu, Linxia.

In: Journal of Visualized Experiments, No. 63, e3945, 08.05.2012.

Research output: Contribution to journalArticle

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