Maternal gestational androgen levels in female marmosets (Callithrix geoffroyi) vary across trimesters but do not vary with the sex ratio of litters

Jeffrey A French, Adam S. Smith, Andrew K. Birnie

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Maternal hormones can dramatically modify offspring phenotypes via organizational actions on morphological and behavioral development. In placental mammals, there is the possibility that some portion of hormones in maternal circulation may be derived from fetal origin. We tested the possibility that maternal androgens in pregnant female marmosets reflected, in part, contributions from male fetuses by comparing levels of urinary androgens across pregnancy in females carrying varying numbers of male offspring. We monitored urinary androgen excretion in 18 pregnancies from five female white-faced marmosets (Callithrix geoffroyi). Androgen levels rose significantly in the first trimester of pregnancy, reached a peak in the middle of the second trimester, and then declined gradually until parturition. At no point in pregnancy were levels of urinary androgens higher in females carrying litters that had 50% or more males than in females carrying litters that were less than 50% male. Levels of maternal androgens were not associated with litter size, the number of males in the litter, or with the proportion of the litter that was male. The high levels of androgen in pregnant females are therefore likely of strictly maternal origin, and any modification of fetal growth and development can be considered a 'maternal effect'.

Original languageEnglish (US)
Pages (from-to)309-314
Number of pages6
JournalGeneral and Comparative Endocrinology
Volume165
Issue number2
DOIs
StatePublished - Jan 15 2010

Fingerprint

Callithrix
Callitrichidae
Sex Ratio
androgens
litters (young animals)
Androgens
sex ratio
Mothers
pregnancy
fetal development
Fetal Development
Pregnancy
hormones
Hormones
Litter Size
Second Pregnancy Trimester
First Pregnancy Trimester
Callithrix geoffroyi
maternal effect
Growth and Development

Keywords

  • Marmoset
  • Maternal effects
  • Pregnancy
  • Sex ratio
  • Testosterone

ASJC Scopus subject areas

  • Animal Science and Zoology
  • Endocrinology

Cite this

Maternal gestational androgen levels in female marmosets (Callithrix geoffroyi) vary across trimesters but do not vary with the sex ratio of litters. / French, Jeffrey A; Smith, Adam S.; Birnie, Andrew K.

In: General and Comparative Endocrinology, Vol. 165, No. 2, 15.01.2010, p. 309-314.

Research output: Contribution to journalArticle

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