MAO-B inhibitors for the treatment of Parkinson’s disease

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Monoamine oxidases (MAO) are crucial enzymes that oxidatively deaminate monoamines (amines that have only one amino group, such as serotonin, epinephrine, norepinephrine, dopamine, tyramine, and tryptamine). There are two main forms of MAO. MAO-A predominates in the gut, spleen, and pancreas, and especially the placenta, and is inhibited by clorgyline [1]. MAO-B predominates in the human brain, skin, and skeletal muscle and is inhibited by deprenyl and pargyline [1]. Recent reviews of MAO inhibitors (MAOI) are available [2].

Original languageEnglish (US)
Title of host publicationParkinson's Disease, Second Edition
PublisherCRC Press
Pages825-838
Number of pages14
ISBN (Electronic)9781439807156
ISBN (Print)9781439807149
DOIs
StatePublished - Jan 1 2012

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Monoamine Oxidase Inhibitors
Monoamine Oxidase
Parkinson Disease
Clorgyline
Pargyline
Selegiline
Tyramine
Placenta
Epinephrine
Amines
Pancreas
Dopamine
Serotonin
Norepinephrine
Skeletal Muscle
Spleen
Skin
Brain
Enzymes

ASJC Scopus subject areas

  • Neuroscience(all)
  • Medicine(all)

Cite this

MAO-B inhibitors for the treatment of Parkinson’s disease. / Bertoni, John M; Torres-Russotto, Diego.

Parkinson's Disease, Second Edition. CRC Press, 2012. p. 825-838.

Research output: Chapter in Book/Report/Conference proceedingChapter

Bertoni, John M ; Torres-Russotto, Diego. / MAO-B inhibitors for the treatment of Parkinson’s disease. Parkinson's Disease, Second Edition. CRC Press, 2012. pp. 825-838
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