Management of traumatic oral-facial injury in the hemophiliac patient with inhibitor: case report.

T. M. Durham, E. D. Hodges, James Lloyd Harper, J. G. Green, F. Tennant

Research output: Contribution to journalReview article

4 Scopus citations


This report describes identification of Factor VIII inhibitor in a patient who then received immune tolerance therapy. The precipitating event was a traumatic orofacial injury that was nonresponsive to traditional factor-replacement therapies. An inhibitor complicates medical and dental management of the hemophiliac patient because it counteracts usual techniques of hemorrhage control using coagulation agents derived from Factor VIII (Monoclate--Armour, Blue Bell, PA). Successful identification and management of the inhibitor patient require communication and consultation between the physician and dentist, up-to-date knowledge regarding the hemophiliac patient's bleeding and infusion history and aggressive application of local adjunctive hemostatic therapies.

Original languageEnglish (US)
Pages (from-to)282-287
Number of pages6
JournalPediatric dentistry
Issue number4
Publication statusPublished - Jul 1 1993


ASJC Scopus subject areas

  • Dentistry(all)

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