Magnetite nanoparticles for medical MR imaging

Zachary R. Stephen, Forrest M. Kievit, Miqin Zhang

Research output: Contribution to journalArticle

172 Citations (Scopus)

Abstract

Nanotechnology has given scientists new tools for the development of advanced materials for the detection and diagnosis of disease. In particular, superparamagnetic iron oxide nanoparticles (SPIONs) have been extensively investigated as novel magnetic resonance imaging (MRI) contrast agents due to a combination of favorable superparamagnetic properties, biodegradability, and surface properties. This review discusses the basics of MR imaging, the origin of SPION's unique magnetic properties, recent developments in MRI acquisition methods for detection of SPIONs, synthesis and post-synthesis processes that improve SPION's imaging characteristics, and the outlook of the translational potential of SPIONs.

Original languageEnglish (US)
Pages (from-to)330-338
Number of pages9
JournalMaterials Today
Volume14
Issue number7-8
DOIs
StatePublished - Jan 1 2011

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Magnetite Nanoparticles
Magnetite nanoparticles
iron oxides
magnetite
Iron oxides
Imaging techniques
nanoparticles
magnetic resonance
Magnetic resonance
Nanoparticles
biodegradability
synthesis
nanotechnology
surface properties
Biodegradability
acquisition
Nanotechnology
Contrast Media
magnetic properties
Surface properties

ASJC Scopus subject areas

  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanics of Materials
  • Mechanical Engineering

Cite this

Magnetite nanoparticles for medical MR imaging. / Stephen, Zachary R.; Kievit, Forrest M.; Zhang, Miqin.

In: Materials Today, Vol. 14, No. 7-8, 01.01.2011, p. 330-338.

Research output: Contribution to journalArticle

Stephen, Zachary R. ; Kievit, Forrest M. ; Zhang, Miqin. / Magnetite nanoparticles for medical MR imaging. In: Materials Today. 2011 ; Vol. 14, No. 7-8. pp. 330-338.
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