Magnetic resonance imaging of acute appendicitis in pregnancy: A 5-year multiinstitutional study

Lauren M.B. Burke, Mustafa R. Bashir, Frank H. Miller, Evan S. Siegelman, Michele Brown, Mamdoh Alobaidy, Tracy A. Jaffe, Shahid M. Hussain, Suzanne L. Palmer, Bonnie L. Garon, Aytekin Oto, Caroline Reinhold, Susan M. Ascher, Danielle K. Demulder, Stephen Thomas, Shaun Best, James Borer, Ken Zhao, Fanny Pinel-Giroux, Isabela De OliveiraDaniel Resende, Richard C. Semelka

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

Objective The purpose of this study was to determine the diagnostic performance of magnetic resonance imaging (MRI) in the diagnosis of acute appendicitis during pregnancy in a multiinstitutional study. Study Design In this multicenter retrospective study, the cases of pregnant women who underwent MRI evaluation of abdominal or pelvic pain and who had clinical suspicion of acute appendicitis between June 1, 2009, and July 31, 2014, were reviewed. All MRI examinations with positive findings for acute appendicitis were confirmed with surgical pathologic information. Sensitivity, specificity, negative predictive values, and positive predictive values were calculated. Receiver operating characteristic curves were generated, and area under the curve analysis was performed for each participating institution. Results Of the cases that were evaluated, 9.3% (66/709) had MRI findings of acute appendicitis. Sensitivity, specificity, accuracy, positive predictive value, and negative predictive values were 96.8%, 99.2%, 99.0%, 92.4%, and 99.7%, respectively. There was no statistically significant difference between centers that were included in the study (pair-wise probability values ranged from 0.12-0.99). Conclusion MRI is useful and reproducible in the diagnosis of suspected acute appendicitis during pregnancy.

Original languageEnglish (US)
Pages (from-to)693.e1-693.e6
JournalAmerican Journal of Obstetrics and Gynecology
Volume213
Issue number5
DOIs
StatePublished - Nov 2015

Fingerprint

Appendicitis
Magnetic Resonance Imaging
Pregnancy
Sensitivity and Specificity
Pelvic Pain
ROC Curve
Abdominal Pain
Multicenter Studies
Area Under Curve
Pregnant Women
Retrospective Studies

Keywords

  • appendicitis
  • magnetic resonance imaging
  • pregnancy

ASJC Scopus subject areas

  • Obstetrics and Gynecology

Cite this

Burke, L. M. B., Bashir, M. R., Miller, F. H., Siegelman, E. S., Brown, M., Alobaidy, M., ... Semelka, R. C. (2015). Magnetic resonance imaging of acute appendicitis in pregnancy: A 5-year multiinstitutional study. American Journal of Obstetrics and Gynecology, 213(5), 693.e1-693.e6. https://doi.org/10.1016/j.ajog.2015.07.026

Magnetic resonance imaging of acute appendicitis in pregnancy : A 5-year multiinstitutional study. / Burke, Lauren M.B.; Bashir, Mustafa R.; Miller, Frank H.; Siegelman, Evan S.; Brown, Michele; Alobaidy, Mamdoh; Jaffe, Tracy A.; Hussain, Shahid M.; Palmer, Suzanne L.; Garon, Bonnie L.; Oto, Aytekin; Reinhold, Caroline; Ascher, Susan M.; Demulder, Danielle K.; Thomas, Stephen; Best, Shaun; Borer, James; Zhao, Ken; Pinel-Giroux, Fanny; De Oliveira, Isabela; Resende, Daniel; Semelka, Richard C.

In: American Journal of Obstetrics and Gynecology, Vol. 213, No. 5, 11.2015, p. 693.e1-693.e6.

Research output: Contribution to journalArticle

Burke, LMB, Bashir, MR, Miller, FH, Siegelman, ES, Brown, M, Alobaidy, M, Jaffe, TA, Hussain, SM, Palmer, SL, Garon, BL, Oto, A, Reinhold, C, Ascher, SM, Demulder, DK, Thomas, S, Best, S, Borer, J, Zhao, K, Pinel-Giroux, F, De Oliveira, I, Resende, D & Semelka, RC 2015, 'Magnetic resonance imaging of acute appendicitis in pregnancy: A 5-year multiinstitutional study', American Journal of Obstetrics and Gynecology, vol. 213, no. 5, pp. 693.e1-693.e6. https://doi.org/10.1016/j.ajog.2015.07.026
Burke, Lauren M.B. ; Bashir, Mustafa R. ; Miller, Frank H. ; Siegelman, Evan S. ; Brown, Michele ; Alobaidy, Mamdoh ; Jaffe, Tracy A. ; Hussain, Shahid M. ; Palmer, Suzanne L. ; Garon, Bonnie L. ; Oto, Aytekin ; Reinhold, Caroline ; Ascher, Susan M. ; Demulder, Danielle K. ; Thomas, Stephen ; Best, Shaun ; Borer, James ; Zhao, Ken ; Pinel-Giroux, Fanny ; De Oliveira, Isabela ; Resende, Daniel ; Semelka, Richard C. / Magnetic resonance imaging of acute appendicitis in pregnancy : A 5-year multiinstitutional study. In: American Journal of Obstetrics and Gynecology. 2015 ; Vol. 213, No. 5. pp. 693.e1-693.e6.
@article{98e05901da9142c0b352d2f864503213,
title = "Magnetic resonance imaging of acute appendicitis in pregnancy: A 5-year multiinstitutional study",
abstract = "Objective The purpose of this study was to determine the diagnostic performance of magnetic resonance imaging (MRI) in the diagnosis of acute appendicitis during pregnancy in a multiinstitutional study. Study Design In this multicenter retrospective study, the cases of pregnant women who underwent MRI evaluation of abdominal or pelvic pain and who had clinical suspicion of acute appendicitis between June 1, 2009, and July 31, 2014, were reviewed. All MRI examinations with positive findings for acute appendicitis were confirmed with surgical pathologic information. Sensitivity, specificity, negative predictive values, and positive predictive values were calculated. Receiver operating characteristic curves were generated, and area under the curve analysis was performed for each participating institution. Results Of the cases that were evaluated, 9.3{\%} (66/709) had MRI findings of acute appendicitis. Sensitivity, specificity, accuracy, positive predictive value, and negative predictive values were 96.8{\%}, 99.2{\%}, 99.0{\%}, 92.4{\%}, and 99.7{\%}, respectively. There was no statistically significant difference between centers that were included in the study (pair-wise probability values ranged from 0.12-0.99). Conclusion MRI is useful and reproducible in the diagnosis of suspected acute appendicitis during pregnancy.",
keywords = "appendicitis, magnetic resonance imaging, pregnancy",
author = "Burke, {Lauren M.B.} and Bashir, {Mustafa R.} and Miller, {Frank H.} and Siegelman, {Evan S.} and Michele Brown and Mamdoh Alobaidy and Jaffe, {Tracy A.} and Hussain, {Shahid M.} and Palmer, {Suzanne L.} and Garon, {Bonnie L.} and Aytekin Oto and Caroline Reinhold and Ascher, {Susan M.} and Demulder, {Danielle K.} and Stephen Thomas and Shaun Best and James Borer and Ken Zhao and Fanny Pinel-Giroux and {De Oliveira}, Isabela and Daniel Resende and Semelka, {Richard C.}",
year = "2015",
month = "11",
doi = "10.1016/j.ajog.2015.07.026",
language = "English (US)",
volume = "213",
pages = "693.e1--693.e6",
journal = "American Journal of Obstetrics and Gynecology",
issn = "0002-9378",
publisher = "Mosby Inc.",
number = "5",

}

TY - JOUR

T1 - Magnetic resonance imaging of acute appendicitis in pregnancy

T2 - A 5-year multiinstitutional study

AU - Burke, Lauren M.B.

AU - Bashir, Mustafa R.

AU - Miller, Frank H.

AU - Siegelman, Evan S.

AU - Brown, Michele

AU - Alobaidy, Mamdoh

AU - Jaffe, Tracy A.

AU - Hussain, Shahid M.

AU - Palmer, Suzanne L.

AU - Garon, Bonnie L.

AU - Oto, Aytekin

AU - Reinhold, Caroline

AU - Ascher, Susan M.

AU - Demulder, Danielle K.

AU - Thomas, Stephen

AU - Best, Shaun

AU - Borer, James

AU - Zhao, Ken

AU - Pinel-Giroux, Fanny

AU - De Oliveira, Isabela

AU - Resende, Daniel

AU - Semelka, Richard C.

PY - 2015/11

Y1 - 2015/11

N2 - Objective The purpose of this study was to determine the diagnostic performance of magnetic resonance imaging (MRI) in the diagnosis of acute appendicitis during pregnancy in a multiinstitutional study. Study Design In this multicenter retrospective study, the cases of pregnant women who underwent MRI evaluation of abdominal or pelvic pain and who had clinical suspicion of acute appendicitis between June 1, 2009, and July 31, 2014, were reviewed. All MRI examinations with positive findings for acute appendicitis were confirmed with surgical pathologic information. Sensitivity, specificity, negative predictive values, and positive predictive values were calculated. Receiver operating characteristic curves were generated, and area under the curve analysis was performed for each participating institution. Results Of the cases that were evaluated, 9.3% (66/709) had MRI findings of acute appendicitis. Sensitivity, specificity, accuracy, positive predictive value, and negative predictive values were 96.8%, 99.2%, 99.0%, 92.4%, and 99.7%, respectively. There was no statistically significant difference between centers that were included in the study (pair-wise probability values ranged from 0.12-0.99). Conclusion MRI is useful and reproducible in the diagnosis of suspected acute appendicitis during pregnancy.

AB - Objective The purpose of this study was to determine the diagnostic performance of magnetic resonance imaging (MRI) in the diagnosis of acute appendicitis during pregnancy in a multiinstitutional study. Study Design In this multicenter retrospective study, the cases of pregnant women who underwent MRI evaluation of abdominal or pelvic pain and who had clinical suspicion of acute appendicitis between June 1, 2009, and July 31, 2014, were reviewed. All MRI examinations with positive findings for acute appendicitis were confirmed with surgical pathologic information. Sensitivity, specificity, negative predictive values, and positive predictive values were calculated. Receiver operating characteristic curves were generated, and area under the curve analysis was performed for each participating institution. Results Of the cases that were evaluated, 9.3% (66/709) had MRI findings of acute appendicitis. Sensitivity, specificity, accuracy, positive predictive value, and negative predictive values were 96.8%, 99.2%, 99.0%, 92.4%, and 99.7%, respectively. There was no statistically significant difference between centers that were included in the study (pair-wise probability values ranged from 0.12-0.99). Conclusion MRI is useful and reproducible in the diagnosis of suspected acute appendicitis during pregnancy.

KW - appendicitis

KW - magnetic resonance imaging

KW - pregnancy

UR - http://www.scopus.com/inward/record.url?scp=84946074510&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84946074510&partnerID=8YFLogxK

U2 - 10.1016/j.ajog.2015.07.026

DO - 10.1016/j.ajog.2015.07.026

M3 - Article

C2 - 26215327

AN - SCOPUS:84946074510

VL - 213

SP - 693.e1-693.e6

JO - American Journal of Obstetrics and Gynecology

JF - American Journal of Obstetrics and Gynecology

SN - 0002-9378

IS - 5

ER -