Abstract
Focussed femtosecond laser pulses are applied in ophthalmic tissues to create an optical breakdown and therefore a tissue dissection through photodisruption. The threshold irradiance for the optical breakdown depends on the photon density in the focal volume which can be influenced by the pulse energy, the size of the irradiated area (focus), and the irradiation time. For an application in the posterior eye segment the aberrations of the anterior eye elements cause a distortion of the wavefront and therefore an increased focal volume which reduces the photon density and thus raises the required energy for surpassing the threshold irradiance. The influence of adaptive optics on lowering the pulse energy required for photodisruption by refining a distorted focus was investigated. A reduction of the threshold energy can be shown when using adaptive optics. The spatial confinement with adaptive optics furthermore raises the irradiance at constant pulse energy. The lowered threshold energy allows for tissue dissection with reduced peripheral damage. This offers the possibility for moving femtosecond laser surgery from corneal or lental applications in the anterior eye to vitreal or retinal applications in the posterior eye.
| Original language | English (US) |
|---|---|
| Title of host publication | Ophthalmic Technologies XXI |
| DOIs | |
| State | Published - Apr 1 2011 |
| Event | Ophthalmic Technologies XXI - San Francisco, CA, United States Duration: Jan 22 2011 → Jan 24 2011 |
Publication series
| Name | Progress in Biomedical Optics and Imaging - Proceedings of SPIE |
|---|---|
| Volume | 7885 |
| ISSN (Print) | 1605-7422 |
Conference
| Conference | Ophthalmic Technologies XXI |
|---|---|
| Country | United States |
| City | San Francisco, CA |
| Period | 1/22/11 → 1/24/11 |
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Keywords
- Adaptive optics
- aberrations
- femtosecond laser
- laser beam shaping
- laser surgery
- ophthalmology
- optical breakdown
- photodisruption
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Biomaterials
- Atomic and Molecular Physics, and Optics
- Radiology Nuclear Medicine and imaging
Cite this
Lowering threshold energy for femtosecond laser pulse photodisruption through turbid media using adaptive optics. / Hansen, A.; Ripken, Tammo; Krueger, Ronald R.; Lubatschowski, Holger.
Ophthalmic Technologies XXI. 2011. 78850Q (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 7885).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Lowering threshold energy for femtosecond laser pulse photodisruption through turbid media using adaptive optics
AU - Hansen, A.
AU - Ripken, Tammo
AU - Krueger, Ronald R.
AU - Lubatschowski, Holger
PY - 2011/4/1
Y1 - 2011/4/1
N2 - Focussed femtosecond laser pulses are applied in ophthalmic tissues to create an optical breakdown and therefore a tissue dissection through photodisruption. The threshold irradiance for the optical breakdown depends on the photon density in the focal volume which can be influenced by the pulse energy, the size of the irradiated area (focus), and the irradiation time. For an application in the posterior eye segment the aberrations of the anterior eye elements cause a distortion of the wavefront and therefore an increased focal volume which reduces the photon density and thus raises the required energy for surpassing the threshold irradiance. The influence of adaptive optics on lowering the pulse energy required for photodisruption by refining a distorted focus was investigated. A reduction of the threshold energy can be shown when using adaptive optics. The spatial confinement with adaptive optics furthermore raises the irradiance at constant pulse energy. The lowered threshold energy allows for tissue dissection with reduced peripheral damage. This offers the possibility for moving femtosecond laser surgery from corneal or lental applications in the anterior eye to vitreal or retinal applications in the posterior eye.
AB - Focussed femtosecond laser pulses are applied in ophthalmic tissues to create an optical breakdown and therefore a tissue dissection through photodisruption. The threshold irradiance for the optical breakdown depends on the photon density in the focal volume which can be influenced by the pulse energy, the size of the irradiated area (focus), and the irradiation time. For an application in the posterior eye segment the aberrations of the anterior eye elements cause a distortion of the wavefront and therefore an increased focal volume which reduces the photon density and thus raises the required energy for surpassing the threshold irradiance. The influence of adaptive optics on lowering the pulse energy required for photodisruption by refining a distorted focus was investigated. A reduction of the threshold energy can be shown when using adaptive optics. The spatial confinement with adaptive optics furthermore raises the irradiance at constant pulse energy. The lowered threshold energy allows for tissue dissection with reduced peripheral damage. This offers the possibility for moving femtosecond laser surgery from corneal or lental applications in the anterior eye to vitreal or retinal applications in the posterior eye.
KW - Adaptive optics
KW - aberrations
KW - femtosecond laser
KW - laser beam shaping
KW - laser surgery
KW - ophthalmology
KW - optical breakdown
KW - photodisruption
UR - http://www.scopus.com/inward/record.url?scp=79953153185&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=79953153185&partnerID=8YFLogxK
U2 - 10.1117/12.873838
DO - 10.1117/12.873838
M3 - Conference contribution
AN - SCOPUS:79953153185
SN - 9780819484222
T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE
BT - Ophthalmic Technologies XXI
ER -