Low grade peritoneal mucinous carcinomatosis associated with human papilloma virus infection: case report.

Zoran Gatalica, Jason M. Foster, Brian W. Loggie

Research output: Contribution to journalArticle

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Pseudomyxoma peritonei is a clinical syndrome characterized by peritoneal dissemination of a mucinous tumor with mucinous ascites. The vast majority of the pseudomyxoma peritonei are associated with mucinous neoplasms of the appendix. We describe a case of pseudomyxoma peritonei associated with mucinous adenocarcinoma of the cervix in a 60-year-old woman. The patient developed low grade mucinous peritoneal carcinomatosis 8 years after hysterectomy for cervical adenocarcinoma. No other primary mucinous tumor was identified and peritoneal carcinomatosis tested positive for high-risk human papilloma virus (HPV), showing both integrated and episomal pattern. HPV has been previously associated with development of cervical carcinomas (both squamous and mucinous) but neither has cervical adenocarcinoma nor HPV been implicated in development of pseudomyxoma peritonei. To the best of our knowledge, this is the first description of HPV-associated malignancy presenting as pseudomyxoma peritonei.

Original languageEnglish (US)
Pages (from-to)669-673
Number of pages5
JournalCroatian medical journal
Issue number5
StatePublished - Oct 2008


ASJC Scopus subject areas

  • Medicine(all)

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