Longitudinal incidence of adverse outcomes of age-related macular degeneration

Ashley Wysong, Paul P. Lee, Frank A. Sloan

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

Objective: To describe the visual, functional, and general health complication rates associated with age-related macular degeneration (AMD) in a nationally representative longitudinal sample of elderly persons. Methods: This is a longitudinal retrospective cohort study (January 1, 1994-December 31, 2004) that used Medicare claims data. We identified beneficiaries aged 68 years and older who had newly diagnosed AMD in 1994 (n = 32 702) and age-, sex-, and race-matched controls who had routine eye surveillance and no diagnosis of AMD throughout the observational period (n = 32 702). Main outcome measures included cumulative incidence of vision loss, blindness, hip fracture, depression, and nursing home placement and prevalence of 16 general health conditions. Results: Elderly individuals with newly diagnosed AMD had higher rates of blindness, vision loss, depression, hip fracture, and residence in a nursing home than those without AMD during a 10-year follow-up period. Individuals with AMD also had a higher prevalence of 11 of 16 general health conditions compared with controls. Conclusions: Individuals aged 68 years and older with AMD had higher rates of visual and functional impairments and had more illness than controls. Our findings demonstrate the substantial resource commitment of caring for the multifaceted health issues of persons diagnosed with AMD.

Original languageEnglish (US)
Pages (from-to)320-327
Number of pages8
JournalArchives of Ophthalmology
Volume127
Issue number3
DOIs
StatePublished - Mar 1 2009

Fingerprint

Macular Degeneration
Incidence
Health
Hip Fractures
Blindness
Nursing Homes
Depression
Vision Disorders
Medicare
Cohort Studies
Retrospective Studies
Outcome Assessment (Health Care)

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Longitudinal incidence of adverse outcomes of age-related macular degeneration. / Wysong, Ashley; Lee, Paul P.; Sloan, Frank A.

In: Archives of Ophthalmology, Vol. 127, No. 3, 01.03.2009, p. 320-327.

Research output: Contribution to journalArticle

Wysong, Ashley ; Lee, Paul P. ; Sloan, Frank A. / Longitudinal incidence of adverse outcomes of age-related macular degeneration. In: Archives of Ophthalmology. 2009 ; Vol. 127, No. 3. pp. 320-327.
@article{2152cda0851b4358acb941b774034a78,
title = "Longitudinal incidence of adverse outcomes of age-related macular degeneration",
abstract = "Objective: To describe the visual, functional, and general health complication rates associated with age-related macular degeneration (AMD) in a nationally representative longitudinal sample of elderly persons. Methods: This is a longitudinal retrospective cohort study (January 1, 1994-December 31, 2004) that used Medicare claims data. We identified beneficiaries aged 68 years and older who had newly diagnosed AMD in 1994 (n = 32 702) and age-, sex-, and race-matched controls who had routine eye surveillance and no diagnosis of AMD throughout the observational period (n = 32 702). Main outcome measures included cumulative incidence of vision loss, blindness, hip fracture, depression, and nursing home placement and prevalence of 16 general health conditions. Results: Elderly individuals with newly diagnosed AMD had higher rates of blindness, vision loss, depression, hip fracture, and residence in a nursing home than those without AMD during a 10-year follow-up period. Individuals with AMD also had a higher prevalence of 11 of 16 general health conditions compared with controls. Conclusions: Individuals aged 68 years and older with AMD had higher rates of visual and functional impairments and had more illness than controls. Our findings demonstrate the substantial resource commitment of caring for the multifaceted health issues of persons diagnosed with AMD.",
author = "Ashley Wysong and Lee, {Paul P.} and Sloan, {Frank A.}",
year = "2009",
month = "3",
day = "1",
doi = "10.1001/archophthalmol.2008.613",
language = "English (US)",
volume = "127",
pages = "320--327",
journal = "JAMA Ophthalmology",
issn = "2168-6165",
publisher = "American Medical Association",
number = "3",

}

TY - JOUR

T1 - Longitudinal incidence of adverse outcomes of age-related macular degeneration

AU - Wysong, Ashley

AU - Lee, Paul P.

AU - Sloan, Frank A.

PY - 2009/3/1

Y1 - 2009/3/1

N2 - Objective: To describe the visual, functional, and general health complication rates associated with age-related macular degeneration (AMD) in a nationally representative longitudinal sample of elderly persons. Methods: This is a longitudinal retrospective cohort study (January 1, 1994-December 31, 2004) that used Medicare claims data. We identified beneficiaries aged 68 years and older who had newly diagnosed AMD in 1994 (n = 32 702) and age-, sex-, and race-matched controls who had routine eye surveillance and no diagnosis of AMD throughout the observational period (n = 32 702). Main outcome measures included cumulative incidence of vision loss, blindness, hip fracture, depression, and nursing home placement and prevalence of 16 general health conditions. Results: Elderly individuals with newly diagnosed AMD had higher rates of blindness, vision loss, depression, hip fracture, and residence in a nursing home than those without AMD during a 10-year follow-up period. Individuals with AMD also had a higher prevalence of 11 of 16 general health conditions compared with controls. Conclusions: Individuals aged 68 years and older with AMD had higher rates of visual and functional impairments and had more illness than controls. Our findings demonstrate the substantial resource commitment of caring for the multifaceted health issues of persons diagnosed with AMD.

AB - Objective: To describe the visual, functional, and general health complication rates associated with age-related macular degeneration (AMD) in a nationally representative longitudinal sample of elderly persons. Methods: This is a longitudinal retrospective cohort study (January 1, 1994-December 31, 2004) that used Medicare claims data. We identified beneficiaries aged 68 years and older who had newly diagnosed AMD in 1994 (n = 32 702) and age-, sex-, and race-matched controls who had routine eye surveillance and no diagnosis of AMD throughout the observational period (n = 32 702). Main outcome measures included cumulative incidence of vision loss, blindness, hip fracture, depression, and nursing home placement and prevalence of 16 general health conditions. Results: Elderly individuals with newly diagnosed AMD had higher rates of blindness, vision loss, depression, hip fracture, and residence in a nursing home than those without AMD during a 10-year follow-up period. Individuals with AMD also had a higher prevalence of 11 of 16 general health conditions compared with controls. Conclusions: Individuals aged 68 years and older with AMD had higher rates of visual and functional impairments and had more illness than controls. Our findings demonstrate the substantial resource commitment of caring for the multifaceted health issues of persons diagnosed with AMD.

UR - http://www.scopus.com/inward/record.url?scp=62449175734&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=62449175734&partnerID=8YFLogxK

U2 - 10.1001/archophthalmol.2008.613

DO - 10.1001/archophthalmol.2008.613

M3 - Article

C2 - 19273797

AN - SCOPUS:62449175734

VL - 127

SP - 320

EP - 327

JO - JAMA Ophthalmology

JF - JAMA Ophthalmology

SN - 2168-6165

IS - 3

ER -