Long-term followup of all patients with muscle invasive (stages T2, T3 and T4) bladder carcinoma in a geographical region

Sten Holmäng, Hans Hedelin, Claes Anderström, Sonny L. Johansson

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

Purpose: We studied the relationship between long-term survival and treatment of stages T2, T3 and T4 bladder carcinoma in an unselected patient population. Materials and Methods: A total of 680 patients with the initial diagnosis of bladder carcinoma in 1987 to 1988 in Western Sweden was prospectively registered and followed until 1994. Of these patients 107 had stage T2 to T3 and 41 had stage T4 disease. Results: Of the patients with stage T2 to T3 disease 30 (mean age 66) underwent radical cystectomy, 33 (mean age 75) full dose radiotherapy and 44 (mean age 81) nonradical therapy (mainly transurethral resection of the bladder). The 5-year crude survival rates were 33, 15 and 14%, respectively. Of the patients with stage T4 disease 6 (mean age 61) underwent radical cystectomy, 9 (mean age 73) full dose radiotherapy and 26 (mean age 81) nonradical therapy (mainly transurethral resection of the bladder). All except 1 patient died of disease within 4 years. Conclusions: More than 60% of the patients in the cohort were considered unsuitable for radical cystectomy and their survival was poor, whether treated with full dose radiotherapy or transurethral resection of the bladder alone.

Original languageEnglish (US)
Pages (from-to)389-392
Number of pages4
JournalJournal of Urology
Volume158
Issue number2
DOIs
StatePublished - Aug 1997

Fingerprint

Urinary Bladder
Carcinoma
Muscles
Cystectomy
Radiotherapy
Survival
Sweden
Therapeutics
Survival Rate
Population

Keywords

  • Bladder diseases
  • Bladder neoplasms
  • Carcinoma
  • Cystectomy
  • Radiotherapy

ASJC Scopus subject areas

  • Urology

Cite this

Long-term followup of all patients with muscle invasive (stages T2, T3 and T4) bladder carcinoma in a geographical region. / Holmäng, Sten; Hedelin, Hans; Anderström, Claes; Johansson, Sonny L.

In: Journal of Urology, Vol. 158, No. 2, 08.1997, p. 389-392.

Research output: Contribution to journalArticle

Holmäng, Sten ; Hedelin, Hans ; Anderström, Claes ; Johansson, Sonny L. / Long-term followup of all patients with muscle invasive (stages T2, T3 and T4) bladder carcinoma in a geographical region. In: Journal of Urology. 1997 ; Vol. 158, No. 2. pp. 389-392.
@article{7d7043fa12a249c9b4d94b588214336a,
title = "Long-term followup of all patients with muscle invasive (stages T2, T3 and T4) bladder carcinoma in a geographical region",
abstract = "Purpose: We studied the relationship between long-term survival and treatment of stages T2, T3 and T4 bladder carcinoma in an unselected patient population. Materials and Methods: A total of 680 patients with the initial diagnosis of bladder carcinoma in 1987 to 1988 in Western Sweden was prospectively registered and followed until 1994. Of these patients 107 had stage T2 to T3 and 41 had stage T4 disease. Results: Of the patients with stage T2 to T3 disease 30 (mean age 66) underwent radical cystectomy, 33 (mean age 75) full dose radiotherapy and 44 (mean age 81) nonradical therapy (mainly transurethral resection of the bladder). The 5-year crude survival rates were 33, 15 and 14{\%}, respectively. Of the patients with stage T4 disease 6 (mean age 61) underwent radical cystectomy, 9 (mean age 73) full dose radiotherapy and 26 (mean age 81) nonradical therapy (mainly transurethral resection of the bladder). All except 1 patient died of disease within 4 years. Conclusions: More than 60{\%} of the patients in the cohort were considered unsuitable for radical cystectomy and their survival was poor, whether treated with full dose radiotherapy or transurethral resection of the bladder alone.",
keywords = "Bladder diseases, Bladder neoplasms, Carcinoma, Cystectomy, Radiotherapy",
author = "Sten Holm{\"a}ng and Hans Hedelin and Claes Anderstr{\"o}m and Johansson, {Sonny L.}",
year = "1997",
month = "8",
doi = "10.1016/S0022-5347(01)64486-0",
language = "English (US)",
volume = "158",
pages = "389--392",
journal = "Journal of Urology",
issn = "0022-5347",
publisher = "Elsevier Inc.",
number = "2",

}

TY - JOUR

T1 - Long-term followup of all patients with muscle invasive (stages T2, T3 and T4) bladder carcinoma in a geographical region

AU - Holmäng, Sten

AU - Hedelin, Hans

AU - Anderström, Claes

AU - Johansson, Sonny L.

PY - 1997/8

Y1 - 1997/8

N2 - Purpose: We studied the relationship between long-term survival and treatment of stages T2, T3 and T4 bladder carcinoma in an unselected patient population. Materials and Methods: A total of 680 patients with the initial diagnosis of bladder carcinoma in 1987 to 1988 in Western Sweden was prospectively registered and followed until 1994. Of these patients 107 had stage T2 to T3 and 41 had stage T4 disease. Results: Of the patients with stage T2 to T3 disease 30 (mean age 66) underwent radical cystectomy, 33 (mean age 75) full dose radiotherapy and 44 (mean age 81) nonradical therapy (mainly transurethral resection of the bladder). The 5-year crude survival rates were 33, 15 and 14%, respectively. Of the patients with stage T4 disease 6 (mean age 61) underwent radical cystectomy, 9 (mean age 73) full dose radiotherapy and 26 (mean age 81) nonradical therapy (mainly transurethral resection of the bladder). All except 1 patient died of disease within 4 years. Conclusions: More than 60% of the patients in the cohort were considered unsuitable for radical cystectomy and their survival was poor, whether treated with full dose radiotherapy or transurethral resection of the bladder alone.

AB - Purpose: We studied the relationship between long-term survival and treatment of stages T2, T3 and T4 bladder carcinoma in an unselected patient population. Materials and Methods: A total of 680 patients with the initial diagnosis of bladder carcinoma in 1987 to 1988 in Western Sweden was prospectively registered and followed until 1994. Of these patients 107 had stage T2 to T3 and 41 had stage T4 disease. Results: Of the patients with stage T2 to T3 disease 30 (mean age 66) underwent radical cystectomy, 33 (mean age 75) full dose radiotherapy and 44 (mean age 81) nonradical therapy (mainly transurethral resection of the bladder). The 5-year crude survival rates were 33, 15 and 14%, respectively. Of the patients with stage T4 disease 6 (mean age 61) underwent radical cystectomy, 9 (mean age 73) full dose radiotherapy and 26 (mean age 81) nonradical therapy (mainly transurethral resection of the bladder). All except 1 patient died of disease within 4 years. Conclusions: More than 60% of the patients in the cohort were considered unsuitable for radical cystectomy and their survival was poor, whether treated with full dose radiotherapy or transurethral resection of the bladder alone.

KW - Bladder diseases

KW - Bladder neoplasms

KW - Carcinoma

KW - Cystectomy

KW - Radiotherapy

UR - http://www.scopus.com/inward/record.url?scp=0342378086&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0342378086&partnerID=8YFLogxK

U2 - 10.1016/S0022-5347(01)64486-0

DO - 10.1016/S0022-5347(01)64486-0

M3 - Article

C2 - 9224309

AN - SCOPUS:0342378086

VL - 158

SP - 389

EP - 392

JO - Journal of Urology

JF - Journal of Urology

SN - 0022-5347

IS - 2

ER -