Liver transplantation for hepatocellular carcinoma: An update

Jean F. Botha, Alan Norman Langnas

Research output: Contribution to journalArticle

15 Scopus citations


Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related death worldwide and the most common primary hepatic malignancy. It arises on a background of hepatic cirrhosis in approximately 95% of the cases in the United States. A wide variety of treatment modalities have been applied in the treatment of HCC. Liver transplantation has emerged as the preferred treatment for patients with small HCC. Transplantation for patients whose tumors do not exceed the Milan criteria yields results equivalent to those of transplantation for non-HCC indications. Controversy now exists regarding the use of living donors, expansion of selection criteria, and role of adjuvant therapy.

Original languageEnglish (US)
Pages (from-to)762-767
Number of pages6
JournalJNCCN Journal of the National Comprehensive Cancer Network
Issue number8
Publication statusPublished - Sep 2006



  • Adjuvant therapy
  • Hepatocellular carcinoma
  • Liver transplantation
  • Living donors

ASJC Scopus subject areas

  • Oncology

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