Two patients with infantile autism by DSM-III criteria and with atypical bipolar symptomatology were treated with lithium carbonate. Both children demonstrated a significant response with levels above 1.0mEq/liter. Factors that may be useful in discovering patients with autism who may respond to lithium treatment include a family history of bipolar illness; extreme hyperactivity not responsive to a stimulant; a definite cyclic component to symptomatic behaviors; sustained laughter, irritability, or giddiness that is not stereotypic; and/or the presence of many or all of the symptom criteria for bipolar disorder.
|Original language||English (US)|
|Number of pages||5|
|Journal||Journal of Clinical Psychopharmacology|
|Publication status||Published - Dec 1987|
ASJC Scopus subject areas
- Psychiatry and Mental health
- Pharmacology (medical)