Late-onset Tay-Sachs disease: Adverse effects of medications and implications for treatment

B. E. Shapiro, S. Hatters-Friedman, J. A. Fernandes-Filho, K. Anthony, M. R. Natowicz

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

The authors conducted a retrospective and brief prospective study of adverse effects of approximately 350 medications in 44 adults with late-onset Tay-Sachs disease (LOTS). Some medications were relatively safe, whereas others, particularly haloperidol, risperidone, and chlorpromazine, were associated with neurologic worsening.

Original languageEnglish (US)
Pages (from-to)875-877
Number of pages3
JournalNeurology
Volume67
Issue number5
DOIs
StatePublished - Sep 1 2006

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Tay-Sachs Disease
Risperidone
Chlorpromazine
Haloperidol
Nervous System
Prospective Studies

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Late-onset Tay-Sachs disease : Adverse effects of medications and implications for treatment. / Shapiro, B. E.; Hatters-Friedman, S.; Fernandes-Filho, J. A.; Anthony, K.; Natowicz, M. R.

In: Neurology, Vol. 67, No. 5, 01.09.2006, p. 875-877.

Research output: Contribution to journalArticle

Shapiro, B. E. ; Hatters-Friedman, S. ; Fernandes-Filho, J. A. ; Anthony, K. ; Natowicz, M. R. / Late-onset Tay-Sachs disease : Adverse effects of medications and implications for treatment. In: Neurology. 2006 ; Vol. 67, No. 5. pp. 875-877.
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