Lack of adherence with the analgesic regimen: A significant barrier to effective cancer pain management

C. Miaskowski, M. J. Dodd, C. West, S. M. Paul, D. Tripathy, P. Koo, K. Schumacher

Research output: Contribution to journalArticle

175 Scopus citations

Abstract

Purpose: To evaluate oncology outpatients' level of adherence to their analgesic regimen during a 5-week period. Patients and Methods: A random sample of 65 adult oncology outpatients with a Karnofsky performance status score of ≥ 50, an average pain intensity score of ≥ 2.5, and radiographic evidence of bone metastasis were recruited for this longitudinal study from seven outpatient settings. On a daily basis, patients rated their level of pain intensity and recorded pain medication intake. Adherence rates for opioid analgesics prescribed on an around-the-clock (ATC) and on an as-needed (PRN) basis were calculated on a weekly basis. Results: Overall adherence rates for ATC opioid analgesics ranged from 84.5% to 90.8% and, for PRN analgesics, from 22.2% to 26.6%. No significant differences over time were found in either of these adherence rates. Conclusion: One factor that seems to contribute to ineffective cancer pain management is poor adherence to the analgesic regimen.

Original languageEnglish (US)
Pages (from-to)4275-4279
Number of pages5
JournalJournal of Clinical Oncology
Volume19
Issue number23
DOIs
Publication statusPublished - Dec 1 2001

    Fingerprint

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Cite this

Miaskowski, C., Dodd, M. J., West, C., Paul, S. M., Tripathy, D., Koo, P., & Schumacher, K. (2001). Lack of adherence with the analgesic regimen: A significant barrier to effective cancer pain management. Journal of Clinical Oncology, 19(23), 4275-4279. https://doi.org/10.1200/JCO.2001.19.23.4275