Key articles and guidelines in the management of acute coronary syndrome and in percutaneous coronary intervention: 2012 Update

Paul P. Dobesh, Craig J. Beavers, Holly R. Herring, Sarah A. Spinler, Zachary A. Stacy, Toby C. Trujillo

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

More than 1 million people in the United States experience an acute coronary syndrome (ACS) every year, and almost 600,000 undergo percutaneous coronary intervention (PCI) for treatment of cardiovascular disease. There is a large amount of evidence-based literature to guide appropriate management of these patients. There have been a number of advances in the treatment of these patients over the last several years. Due to the large amount of rapidly available literature concerning the care of patients with ACS or undergoing PCI, clinicians can often find it difficult to keep up with the information needed for optimizing care of these patients. Therefore, we provide the second update to the first compiled bibliography of key articles and guidelines relative to patients with ACS published in Pharmacotherapy in 2004. The initial update was published in Pharmacotherapy in 2007 and also included bibliographies concerning management of patients undergoing PCI. A number of guidelines and practice-changing literature have been published since the update in 2007. Specific areas included in this review are updated summaries of clinical practice guidelines and clinical trials of anticoagulants, antiplatelets, platelet aggregation testing, pharmacogenomics testing in patients taking clopidogrel, clopidogrel loading dose comparisons, clopidogrel and proton pump inhibitor drug interactions, the impact of bleeding in ACS, and statins. As with previous versions of this document, we hope that this compilation will serve as a resource for pharmacists, physicians, nurses, residents, and students responsible for the care of patients with coronary heart disease.

Original languageEnglish (US)
Pages (from-to)e348-e386
JournalPharmacotherapy
Volume32
Issue number12
DOIs
StatePublished - Dec 1 2012

Fingerprint

clopidogrel
Percutaneous Coronary Intervention
Acute Coronary Syndrome
Guidelines
Patient Care
Bibliography
Practice Guidelines
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Drug Therapy
Proton Pump Inhibitors
Drug Interactions
Platelet Aggregation
Pharmacists
Anticoagulants
Coronary Disease
Cardiovascular Diseases
Nurses
Clinical Trials
Hemorrhage
Students

Keywords

  • ACS
  • Acute coronary syndrome
  • Cardiovascular disease
  • Guidelines
  • PCI
  • Percutaneous coronary intervention
  • Pharmacotherapy

ASJC Scopus subject areas

  • Pharmacology (medical)

Cite this

Key articles and guidelines in the management of acute coronary syndrome and in percutaneous coronary intervention : 2012 Update. / Dobesh, Paul P.; Beavers, Craig J.; Herring, Holly R.; Spinler, Sarah A.; Stacy, Zachary A.; Trujillo, Toby C.

In: Pharmacotherapy, Vol. 32, No. 12, 01.12.2012, p. e348-e386.

Research output: Contribution to journalArticle

Dobesh, Paul P. ; Beavers, Craig J. ; Herring, Holly R. ; Spinler, Sarah A. ; Stacy, Zachary A. ; Trujillo, Toby C. / Key articles and guidelines in the management of acute coronary syndrome and in percutaneous coronary intervention : 2012 Update. In: Pharmacotherapy. 2012 ; Vol. 32, No. 12. pp. e348-e386.
@article{e9bd86951ed342c096e0e8b1b65b52e6,
title = "Key articles and guidelines in the management of acute coronary syndrome and in percutaneous coronary intervention: 2012 Update",
abstract = "More than 1 million people in the United States experience an acute coronary syndrome (ACS) every year, and almost 600,000 undergo percutaneous coronary intervention (PCI) for treatment of cardiovascular disease. There is a large amount of evidence-based literature to guide appropriate management of these patients. There have been a number of advances in the treatment of these patients over the last several years. Due to the large amount of rapidly available literature concerning the care of patients with ACS or undergoing PCI, clinicians can often find it difficult to keep up with the information needed for optimizing care of these patients. Therefore, we provide the second update to the first compiled bibliography of key articles and guidelines relative to patients with ACS published in Pharmacotherapy in 2004. The initial update was published in Pharmacotherapy in 2007 and also included bibliographies concerning management of patients undergoing PCI. A number of guidelines and practice-changing literature have been published since the update in 2007. Specific areas included in this review are updated summaries of clinical practice guidelines and clinical trials of anticoagulants, antiplatelets, platelet aggregation testing, pharmacogenomics testing in patients taking clopidogrel, clopidogrel loading dose comparisons, clopidogrel and proton pump inhibitor drug interactions, the impact of bleeding in ACS, and statins. As with previous versions of this document, we hope that this compilation will serve as a resource for pharmacists, physicians, nurses, residents, and students responsible for the care of patients with coronary heart disease.",
keywords = "ACS, Acute coronary syndrome, Cardiovascular disease, Guidelines, PCI, Percutaneous coronary intervention, Pharmacotherapy",
author = "Dobesh, {Paul P.} and Beavers, {Craig J.} and Herring, {Holly R.} and Spinler, {Sarah A.} and Stacy, {Zachary A.} and Trujillo, {Toby C.}",
year = "2012",
month = "12",
day = "1",
doi = "10.1002/phar.1225",
language = "English (US)",
volume = "32",
pages = "e348--e386",
journal = "Pharmacotherapy",
issn = "0277-0008",
publisher = "Pharmacotherapy Publications Inc.",
number = "12",

}

TY - JOUR

T1 - Key articles and guidelines in the management of acute coronary syndrome and in percutaneous coronary intervention

T2 - 2012 Update

AU - Dobesh, Paul P.

AU - Beavers, Craig J.

AU - Herring, Holly R.

AU - Spinler, Sarah A.

AU - Stacy, Zachary A.

AU - Trujillo, Toby C.

PY - 2012/12/1

Y1 - 2012/12/1

N2 - More than 1 million people in the United States experience an acute coronary syndrome (ACS) every year, and almost 600,000 undergo percutaneous coronary intervention (PCI) for treatment of cardiovascular disease. There is a large amount of evidence-based literature to guide appropriate management of these patients. There have been a number of advances in the treatment of these patients over the last several years. Due to the large amount of rapidly available literature concerning the care of patients with ACS or undergoing PCI, clinicians can often find it difficult to keep up with the information needed for optimizing care of these patients. Therefore, we provide the second update to the first compiled bibliography of key articles and guidelines relative to patients with ACS published in Pharmacotherapy in 2004. The initial update was published in Pharmacotherapy in 2007 and also included bibliographies concerning management of patients undergoing PCI. A number of guidelines and practice-changing literature have been published since the update in 2007. Specific areas included in this review are updated summaries of clinical practice guidelines and clinical trials of anticoagulants, antiplatelets, platelet aggregation testing, pharmacogenomics testing in patients taking clopidogrel, clopidogrel loading dose comparisons, clopidogrel and proton pump inhibitor drug interactions, the impact of bleeding in ACS, and statins. As with previous versions of this document, we hope that this compilation will serve as a resource for pharmacists, physicians, nurses, residents, and students responsible for the care of patients with coronary heart disease.

AB - More than 1 million people in the United States experience an acute coronary syndrome (ACS) every year, and almost 600,000 undergo percutaneous coronary intervention (PCI) for treatment of cardiovascular disease. There is a large amount of evidence-based literature to guide appropriate management of these patients. There have been a number of advances in the treatment of these patients over the last several years. Due to the large amount of rapidly available literature concerning the care of patients with ACS or undergoing PCI, clinicians can often find it difficult to keep up with the information needed for optimizing care of these patients. Therefore, we provide the second update to the first compiled bibliography of key articles and guidelines relative to patients with ACS published in Pharmacotherapy in 2004. The initial update was published in Pharmacotherapy in 2007 and also included bibliographies concerning management of patients undergoing PCI. A number of guidelines and practice-changing literature have been published since the update in 2007. Specific areas included in this review are updated summaries of clinical practice guidelines and clinical trials of anticoagulants, antiplatelets, platelet aggregation testing, pharmacogenomics testing in patients taking clopidogrel, clopidogrel loading dose comparisons, clopidogrel and proton pump inhibitor drug interactions, the impact of bleeding in ACS, and statins. As with previous versions of this document, we hope that this compilation will serve as a resource for pharmacists, physicians, nurses, residents, and students responsible for the care of patients with coronary heart disease.

KW - ACS

KW - Acute coronary syndrome

KW - Cardiovascular disease

KW - Guidelines

KW - PCI

KW - Percutaneous coronary intervention

KW - Pharmacotherapy

UR - http://www.scopus.com/inward/record.url?scp=84871579696&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84871579696&partnerID=8YFLogxK

U2 - 10.1002/phar.1225

DO - 10.1002/phar.1225

M3 - Article

C2 - 23165917

AN - SCOPUS:84871579696

VL - 32

SP - e348-e386

JO - Pharmacotherapy

JF - Pharmacotherapy

SN - 0277-0008

IS - 12

ER -