Isolation and structure of phakellistatin 2 from the eastern indian ocean marine sponge phakellia carteri

George R. Pettit, Rui Tan, Michael D. Williams, Larry Tackett, Jean M. Schmidt, Ronald Cerny, John N A Hooper

Research output: Contribution to journalArticle

44 Citations (Scopus)

Abstract

The marine sponge Phakellia carteri indigenous to the Republic of the Comoros was found to contain a new cell growth inhibitory (P388 cell line ED50 0.34 μg/ml) cyclo-heptapeptide named phakellistatin 2.

Original languageEnglish (US)
Pages (from-to)2869-2874
Number of pages6
JournalBioorganic and Medicinal Chemistry Letters
Volume3
Issue number12
DOIs
StatePublished - Jan 1 1993

Fingerprint

Comoros
Indian Ocean
Cell growth
Porifera
Cells
Cell Line
Growth
phakellistatin 2

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmaceutical Science
  • Drug Discovery
  • Clinical Biochemistry
  • Organic Chemistry

Cite this

Isolation and structure of phakellistatin 2 from the eastern indian ocean marine sponge phakellia carteri. / Pettit, George R.; Tan, Rui; Williams, Michael D.; Tackett, Larry; Schmidt, Jean M.; Cerny, Ronald; Hooper, John N A.

In: Bioorganic and Medicinal Chemistry Letters, Vol. 3, No. 12, 01.01.1993, p. 2869-2874.

Research output: Contribution to journalArticle

Pettit, George R. ; Tan, Rui ; Williams, Michael D. ; Tackett, Larry ; Schmidt, Jean M. ; Cerny, Ronald ; Hooper, John N A. / Isolation and structure of phakellistatin 2 from the eastern indian ocean marine sponge phakellia carteri. In: Bioorganic and Medicinal Chemistry Letters. 1993 ; Vol. 3, No. 12. pp. 2869-2874.
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