Is age at symptom onset associated with severity of memory impairment in adults with obsessive-compulsive disorder?

A. Henin, Cary R Savage, S. L. Rauch, T. Deckersbach, S. Wilhelm, L. Baer, M. W. Otto, M. A. Jenike

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Objective: Age at onset is a potentially important marker for neurobiological features of obsessive-compulsive disorder (OCD). This study examined the relationship between age at symptom onset and memory impairment in adults with OCD. Method: The authors used the Rey-Osterrieth Complex Figure Test and the California Verbal Learning Test to compare memory functioning of 37 adult OCD patients with self-reported childhood onset of symptoms (onset at less than 18 years of age) with that of 31 patients with adult-onset symptoms. Results: No differences were found between the two groups on any of the verbal and nonverbal memory measures. Conclusions: Self-reported age at symptom onset is not associated with memory performance in adult patients with OCD according to tests previously found to be sensitive to frontal-striatal system dysfunction and impairment in OCD. Such dysfunction appears to be a consistent feature of OCD in adults, regardless of age at initial symptom onset.

Original languageEnglish (US)
Pages (from-to)137-139
Number of pages3
JournalAmerican Journal of Psychiatry
Volume158
Issue number1
DOIs
StatePublished - Jan 23 2001

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Obsessive-Compulsive Disorder
Age of Onset
Corpus Striatum
Verbal Learning

ASJC Scopus subject areas

  • Psychiatry and Mental health

Cite this

Is age at symptom onset associated with severity of memory impairment in adults with obsessive-compulsive disorder? / Henin, A.; Savage, Cary R; Rauch, S. L.; Deckersbach, T.; Wilhelm, S.; Baer, L.; Otto, M. W.; Jenike, M. A.

In: American Journal of Psychiatry, Vol. 158, No. 1, 23.01.2001, p. 137-139.

Research output: Contribution to journalArticle

Henin, A. ; Savage, Cary R ; Rauch, S. L. ; Deckersbach, T. ; Wilhelm, S. ; Baer, L. ; Otto, M. W. ; Jenike, M. A. / Is age at symptom onset associated with severity of memory impairment in adults with obsessive-compulsive disorder?. In: American Journal of Psychiatry. 2001 ; Vol. 158, No. 1. pp. 137-139.
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