Is a foetus developing in a sterile environment?

T. M. Wassenaar, Pinaki Panigrahi

Research output: Contribution to journalArticle

50 Citations (Scopus)

Abstract

Novel findings in microbiology question the long-standing paradigm that a healthy pregnancy implies a sterile uterus. It now seems that the placenta is frequently colonized with bacteria, and a placental microbiome has been identified. Recent literature findings are summarized here, and an attempt is made to separate pathological bacterial presence from a naturally occurring microbiome.

Original languageEnglish (US)
Pages (from-to)572-579
Number of pages8
JournalLetters in Applied Microbiology
Volume59
Issue number6
DOIs
StatePublished - Dec 1 2014

Fingerprint

Microbiota
Fetus
Microbiology
Placenta
Uterus
Bacteria
Pregnancy

Keywords

  • Amniotic fluid
  • Breast milk
  • Neonatal sepsis
  • Newborn colonization
  • Placenta microbiome
  • Placental microbiome
  • Preterm birth

ASJC Scopus subject areas

  • Applied Microbiology and Biotechnology

Cite this

Is a foetus developing in a sterile environment? / Wassenaar, T. M.; Panigrahi, Pinaki.

In: Letters in Applied Microbiology, Vol. 59, No. 6, 01.12.2014, p. 572-579.

Research output: Contribution to journalArticle

Wassenaar, T. M. ; Panigrahi, Pinaki. / Is a foetus developing in a sterile environment?. In: Letters in Applied Microbiology. 2014 ; Vol. 59, No. 6. pp. 572-579.
@article{dfe9e9a0ec534346b493cb97c3fee661,
title = "Is a foetus developing in a sterile environment?",
abstract = "Novel findings in microbiology question the long-standing paradigm that a healthy pregnancy implies a sterile uterus. It now seems that the placenta is frequently colonized with bacteria, and a placental microbiome has been identified. Recent literature findings are summarized here, and an attempt is made to separate pathological bacterial presence from a naturally occurring microbiome.",
keywords = "Amniotic fluid, Breast milk, Neonatal sepsis, Newborn colonization, Placenta microbiome, Placental microbiome, Preterm birth",
author = "Wassenaar, {T. M.} and Pinaki Panigrahi",
year = "2014",
month = "12",
day = "1",
doi = "10.1111/lam.12334",
language = "English (US)",
volume = "59",
pages = "572--579",
journal = "Letters in Applied Microbiology",
issn = "0266-8254",
publisher = "Wiley-Blackwell",
number = "6",

}

TY - JOUR

T1 - Is a foetus developing in a sterile environment?

AU - Wassenaar, T. M.

AU - Panigrahi, Pinaki

PY - 2014/12/1

Y1 - 2014/12/1

N2 - Novel findings in microbiology question the long-standing paradigm that a healthy pregnancy implies a sterile uterus. It now seems that the placenta is frequently colonized with bacteria, and a placental microbiome has been identified. Recent literature findings are summarized here, and an attempt is made to separate pathological bacterial presence from a naturally occurring microbiome.

AB - Novel findings in microbiology question the long-standing paradigm that a healthy pregnancy implies a sterile uterus. It now seems that the placenta is frequently colonized with bacteria, and a placental microbiome has been identified. Recent literature findings are summarized here, and an attempt is made to separate pathological bacterial presence from a naturally occurring microbiome.

KW - Amniotic fluid

KW - Breast milk

KW - Neonatal sepsis

KW - Newborn colonization

KW - Placenta microbiome

KW - Placental microbiome

KW - Preterm birth

UR - http://www.scopus.com/inward/record.url?scp=84916942144&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84916942144&partnerID=8YFLogxK

U2 - 10.1111/lam.12334

DO - 10.1111/lam.12334

M3 - Article

VL - 59

SP - 572

EP - 579

JO - Letters in Applied Microbiology

JF - Letters in Applied Microbiology

SN - 0266-8254

IS - 6

ER -