Invitro characterization of the impact of selected dietary fibers on fecal microbiota composition and short chain fatty acid production

Junyi Yang, Inés Martínez, Jens Walter, Ali Keshavarzian, Devin J. Rose

Research output: Contribution to journalArticle

79 Citations (Scopus)

Abstract

The effects of six dietary fibers [pectin, guar gum, inulin, arabinoxylan, β-glucan, and resistant starch] on the human fecal microbiota during invitro fermentation were determined. Bifidobacterium increased almost 25% on pectin compared with the control; a significant increase in Bifidobacterium adolescentis type-2 was observed on resistant starch. Bacteroides exhibited a positive correlation with propionate/short chain fatty acid (SCFA) production (r=0.59, p<0.01), while Ruminococcaceae and Faecalibacterium displayed positive correlations with butyrate/SCFA production (r=0.39, 0.54, p<0.01). A negative correlation was detected between inulin utilization and Subdoligranulum (r=-0.73, p≤0.01), while strong positive relationships were found between β-glucan utilization and Firmicutes (r=0.73, p≤0.01) and resistant starch utilization and Blautia wexlerae (r=0.82, p<0.01). Dietary fibers have specific and unique impacts on intestinal microbiota composition and metabolism. These findings provide a rationale for the development of functional ingredients targeted towards a targeted modulation of the gut microbiota.

Original languageEnglish (US)
Pages (from-to)74-81
Number of pages8
JournalAnaerobe
Volume23
DOIs
StatePublished - Oct 1 2013

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Volatile Fatty Acids
Microbiota
Dietary Fiber
Starch
guar gum
Inulin
Glucans
Bacteroides
Bifidobacterium
Butyrates
Propionates
Fermentation
Gastrointestinal Microbiome
pectin

Keywords

  • Arabinoxylan
  • Guar gum
  • Inulin
  • Pectin
  • Resistant starch
  • β-glucan

ASJC Scopus subject areas

  • Microbiology
  • Infectious Diseases

Cite this

Invitro characterization of the impact of selected dietary fibers on fecal microbiota composition and short chain fatty acid production. / Yang, Junyi; Martínez, Inés; Walter, Jens; Keshavarzian, Ali; Rose, Devin J.

In: Anaerobe, Vol. 23, 01.10.2013, p. 74-81.

Research output: Contribution to journalArticle

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