Invasive fungal sinusitis following liver or bone marrow transplantation

Perry James Johnson, W. M. Lydiatt, J. V. Huerter, F. P. Ogren, Julie Marie Vose, R. J. Stratta, A. J. Yonkers

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Invasive fungal infection of the nose and paranasal sinuses occurs almost exclusively in immunocompromised patients and is increasingly recognized as a complication of organ transplantation. We performed a retrospective chart review of 955 bone marrow and 749 liver transplant patients to identify risk factors, presenting signs and symptoms, methods of diagnosis, and successful management strategies. We report on five cases following bone marrow transplantation and one case following liver transplantation. Neutropenia is the single most important risk factor in the development of and recovery from invasive fungal sinusitis. Early diagnosis, combined with antifungal agents, hematopoietic growth factors, and aggressive surgical debridement is the most effective means of management.

Original languageEnglish (US)
Pages (from-to)77-83
Number of pages7
JournalAmerican Journal of Rhinology
Volume8
Issue number2
DOIs
StatePublished - Jan 1 1994

Fingerprint

Sinusitis
Bone Marrow Transplantation
Antifungal Agents
Paranasal Sinuses
Liver
Immunocompromised Host
Organ Transplantation
Debridement
Neutropenia
Nose
Liver Transplantation
Signs and Symptoms
Early Diagnosis
Intercellular Signaling Peptides and Proteins
Bone Marrow
Transplants
Invasive Fungal Infections

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Invasive fungal sinusitis following liver or bone marrow transplantation. / Johnson, Perry James; Lydiatt, W. M.; Huerter, J. V.; Ogren, F. P.; Vose, Julie Marie; Stratta, R. J.; Yonkers, A. J.

In: American Journal of Rhinology, Vol. 8, No. 2, 01.01.1994, p. 77-83.

Research output: Contribution to journalArticle

Johnson, Perry James ; Lydiatt, W. M. ; Huerter, J. V. ; Ogren, F. P. ; Vose, Julie Marie ; Stratta, R. J. ; Yonkers, A. J. / Invasive fungal sinusitis following liver or bone marrow transplantation. In: American Journal of Rhinology. 1994 ; Vol. 8, No. 2. pp. 77-83.
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