Intravenous immunoglobulin in rheumatic disease

L. W. Klassen, L. H. Calabrese, R. M. Laxer

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

With the advent of numerous commerical perparations of intravenous immunoglobulin preparations since 1981, it is now possible to administer these preparations in significant quantities to cause elevation of serum immunoglobulin levels both in patients with antibody-deficient states and in those with normal circulating immunoglobulin levels. This led to a report of dramatic improvement of thrombocytopenia in a child with agammaglobulin following the use of intravenous immunoglobulin preparations for recurrent infections, and further studies in both children and adults with associated symptoms suggested therapeutic efficacy of intravenous immunoglobulin preparations in controlling autoimmune symptoms.

Original languageEnglish (US)
Pages (from-to)155-173
Number of pages19
JournalRheumatic Disease Clinics of North America
Volume22
Issue number1
DOIs
StatePublished - Jan 1 1996

Fingerprint

Intravenous Immunoglobulins
Rheumatic Diseases
Immunoglobulins
Thrombocytopenia
Antibodies
Infection
Serum
Therapeutics

ASJC Scopus subject areas

  • Rheumatology

Cite this

Intravenous immunoglobulin in rheumatic disease. / Klassen, L. W.; Calabrese, L. H.; Laxer, R. M.

In: Rheumatic Disease Clinics of North America, Vol. 22, No. 1, 01.01.1996, p. 155-173.

Research output: Contribution to journalArticle

Klassen, L. W. ; Calabrese, L. H. ; Laxer, R. M. / Intravenous immunoglobulin in rheumatic disease. In: Rheumatic Disease Clinics of North America. 1996 ; Vol. 22, No. 1. pp. 155-173.
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