Intracranial pressure monitors in traumatic brain injury: A systematic review

Asher A. Mendelson, Chris Gillis, William R. Henderson, Juan J. Ronco, Vinay Dhingra, Donald E.G. Griesdale

Research output: Contribution to journalReview article

23 Citations (Scopus)

Abstract

We conducted a systematic review to examine the relationship between intracranial pressure monitors (ICP) monitors and mortality in traumatic brain injury (TBI). We systematically searched for articles that met the following criteria: (1) adults patients, (2) TBI, (3) use of an ICP monitor, (4) point estimate for mortality with ICP monitoring (5) adjustment for potential confounders. Six observational studies were identified with 11,371 patients. There was marked between-study heterogeneity that precluded a pooled analysis. Patients with ICP monitors had different clinical characteristics and received more ICP targeted therapy in the ICU. Four studies found no significant relationship between ICP monitoring and survival, while the other two studies demonstrated conflicting results. Significant confounding by indication in observational studies limits the examination of isolated TBI interventions. More research should focus on interventions that affect TBI careplan systems. Further research is needed to identify which subset of severe TBI patients may benefit from ICP monitoring.

Original languageEnglish (US)
Pages (from-to)571-576
Number of pages6
JournalCanadian Journal of Neurological Sciences
Volume39
Issue number5
DOIs
StatePublished - Sep 1 2012

Fingerprint

Intracranial Pressure
Observational Studies
Mortality
Traumatic Brain Injury
Research
Survival

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

Cite this

Mendelson, A. A., Gillis, C., Henderson, W. R., Ronco, J. J., Dhingra, V., & Griesdale, D. E. G. (2012). Intracranial pressure monitors in traumatic brain injury: A systematic review. Canadian Journal of Neurological Sciences, 39(5), 571-576. https://doi.org/10.1017/S0317167100015286

Intracranial pressure monitors in traumatic brain injury : A systematic review. / Mendelson, Asher A.; Gillis, Chris; Henderson, William R.; Ronco, Juan J.; Dhingra, Vinay; Griesdale, Donald E.G.

In: Canadian Journal of Neurological Sciences, Vol. 39, No. 5, 01.09.2012, p. 571-576.

Research output: Contribution to journalReview article

Mendelson, AA, Gillis, C, Henderson, WR, Ronco, JJ, Dhingra, V & Griesdale, DEG 2012, 'Intracranial pressure monitors in traumatic brain injury: A systematic review', Canadian Journal of Neurological Sciences, vol. 39, no. 5, pp. 571-576. https://doi.org/10.1017/S0317167100015286
Mendelson, Asher A. ; Gillis, Chris ; Henderson, William R. ; Ronco, Juan J. ; Dhingra, Vinay ; Griesdale, Donald E.G. / Intracranial pressure monitors in traumatic brain injury : A systematic review. In: Canadian Journal of Neurological Sciences. 2012 ; Vol. 39, No. 5. pp. 571-576.
@article{2a497626f1c94dbc87f7a4fe287741ec,
title = "Intracranial pressure monitors in traumatic brain injury: A systematic review",
abstract = "We conducted a systematic review to examine the relationship between intracranial pressure monitors (ICP) monitors and mortality in traumatic brain injury (TBI). We systematically searched for articles that met the following criteria: (1) adults patients, (2) TBI, (3) use of an ICP monitor, (4) point estimate for mortality with ICP monitoring (5) adjustment for potential confounders. Six observational studies were identified with 11,371 patients. There was marked between-study heterogeneity that precluded a pooled analysis. Patients with ICP monitors had different clinical characteristics and received more ICP targeted therapy in the ICU. Four studies found no significant relationship between ICP monitoring and survival, while the other two studies demonstrated conflicting results. Significant confounding by indication in observational studies limits the examination of isolated TBI interventions. More research should focus on interventions that affect TBI careplan systems. Further research is needed to identify which subset of severe TBI patients may benefit from ICP monitoring.",
author = "Mendelson, {Asher A.} and Chris Gillis and Henderson, {William R.} and Ronco, {Juan J.} and Vinay Dhingra and Griesdale, {Donald E.G.}",
year = "2012",
month = "9",
day = "1",
doi = "10.1017/S0317167100015286",
language = "English (US)",
volume = "39",
pages = "571--576",
journal = "Canadian Journal of Neurological Sciences",
issn = "0317-1671",
publisher = "Canadian Journal of Neurological Sciences",
number = "5",

}

TY - JOUR

T1 - Intracranial pressure monitors in traumatic brain injury

T2 - A systematic review

AU - Mendelson, Asher A.

AU - Gillis, Chris

AU - Henderson, William R.

AU - Ronco, Juan J.

AU - Dhingra, Vinay

AU - Griesdale, Donald E.G.

PY - 2012/9/1

Y1 - 2012/9/1

N2 - We conducted a systematic review to examine the relationship between intracranial pressure monitors (ICP) monitors and mortality in traumatic brain injury (TBI). We systematically searched for articles that met the following criteria: (1) adults patients, (2) TBI, (3) use of an ICP monitor, (4) point estimate for mortality with ICP monitoring (5) adjustment for potential confounders. Six observational studies were identified with 11,371 patients. There was marked between-study heterogeneity that precluded a pooled analysis. Patients with ICP monitors had different clinical characteristics and received more ICP targeted therapy in the ICU. Four studies found no significant relationship between ICP monitoring and survival, while the other two studies demonstrated conflicting results. Significant confounding by indication in observational studies limits the examination of isolated TBI interventions. More research should focus on interventions that affect TBI careplan systems. Further research is needed to identify which subset of severe TBI patients may benefit from ICP monitoring.

AB - We conducted a systematic review to examine the relationship between intracranial pressure monitors (ICP) monitors and mortality in traumatic brain injury (TBI). We systematically searched for articles that met the following criteria: (1) adults patients, (2) TBI, (3) use of an ICP monitor, (4) point estimate for mortality with ICP monitoring (5) adjustment for potential confounders. Six observational studies were identified with 11,371 patients. There was marked between-study heterogeneity that precluded a pooled analysis. Patients with ICP monitors had different clinical characteristics and received more ICP targeted therapy in the ICU. Four studies found no significant relationship between ICP monitoring and survival, while the other two studies demonstrated conflicting results. Significant confounding by indication in observational studies limits the examination of isolated TBI interventions. More research should focus on interventions that affect TBI careplan systems. Further research is needed to identify which subset of severe TBI patients may benefit from ICP monitoring.

UR - http://www.scopus.com/inward/record.url?scp=84868260986&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84868260986&partnerID=8YFLogxK

U2 - 10.1017/S0317167100015286

DO - 10.1017/S0317167100015286

M3 - Review article

C2 - 22931696

AN - SCOPUS:84868260986

VL - 39

SP - 571

EP - 576

JO - Canadian Journal of Neurological Sciences

JF - Canadian Journal of Neurological Sciences

SN - 0317-1671

IS - 5

ER -