Intestinal Lengthening in Adult Patients with Short Bowel Syndrome

Govardhana Rao Yannam, Debra L. Sudan, Wendy Grant, Jean Botha, Alan Norman Langnas, Jon S Thompson

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

Introduction: Limited information regarding the usefulness of bowel lengthening in adult patients with short bowel syndrome is available. Methods: Retrospective review of a single center series of intestinal lengthening over 15-year period in patients ≥18 years old. Results: Twenty adult patients underwent Bianchi (n = 6) or serial transverse enteroplasty (STEP) (n = 15). Median age was 38 (18-66) years and 11 were female. Indications were (a) to increase the enteral caloric intake thereby reduce or wean parenteral nutrition (PN) (n = 14) or (b) for bacterial overgrowth (n = 6). Twelve patients required additional procedures to relieve the anatomical blockade. Median remnant bowel length prior to surgery, length gained and final bowel length was 60, 20, and 80 cm, respectively. Survival was 90% with mean follow-up of 4.1 years (range = 1-7.9 years). Two patients died during follow-up. Intestinal transplant salvage was required in one patient 4.8 years after STEP. Overall, of 17 patients, ten (59%) patients achieved enteral autonomy and were off PN. Of seven patients who are on PN, three patients showed significant improvement in enteral caloric intake. All except one showed significant improvement in symptoms of bacterial overgrowth. Conclusions: Bowel lengthening is technically feasible and effectively leads to weaning from PN in more than half of the adult patients. Lengthening procedures may be an underutilized treatment for adults with short bowel syndrome.

Original languageEnglish (US)
Pages (from-to)1931-1936
Number of pages6
JournalJournal of Gastrointestinal Surgery
Volume14
Issue number12
DOIs
StatePublished - Dec 1 2010

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Short Bowel Syndrome
Parenteral Nutrition
Small Intestine
Energy Intake
Weaning

Keywords

  • Bowel lengthening in adults
  • Short bowel syndrome
  • TPN dependence

ASJC Scopus subject areas

  • Surgery
  • Gastroenterology

Cite this

Intestinal Lengthening in Adult Patients with Short Bowel Syndrome. / Yannam, Govardhana Rao; Sudan, Debra L.; Grant, Wendy; Botha, Jean; Langnas, Alan Norman; Thompson, Jon S.

In: Journal of Gastrointestinal Surgery, Vol. 14, No. 12, 01.12.2010, p. 1931-1936.

Research output: Contribution to journalArticle

Yannam, Govardhana Rao ; Sudan, Debra L. ; Grant, Wendy ; Botha, Jean ; Langnas, Alan Norman ; Thompson, Jon S. / Intestinal Lengthening in Adult Patients with Short Bowel Syndrome. In: Journal of Gastrointestinal Surgery. 2010 ; Vol. 14, No. 12. pp. 1931-1936.
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