Interventions Targeting Deep Tissue Lymph Nodes May Not Effectively Reduce the Risk of Salmonellosis from Ground Pork Consumption: A Quantitative Microbial Risk Assessment

Yangjunna Zhang, Annette M. O'Connor, Chong Wang, James S. Dickson, H. Scott Hurd, Bing Wang

Research output: Contribution to journalArticle

Abstract

The inclusion of deep tissue lymph nodes (DTLNs) or nonvisceral lymph nodes contaminated with Salmonella in wholesale fresh ground pork (WFGP) production may pose risks to public health. To assess the relative contribution of DTLNs to human salmonellosis occurrence associated with ground pork consumption and to investigate potential critical control points in the slaughter-to-table continuum for the control of human salmonellosis in the United States, a quantitative microbial risk assessment (QMRA) model was established. The model predicted an average of 45 cases of salmonellosis (95% CI = [19, 71]) per 100,000 Americans annually due to WFGP consumption. Sensitivity analysis of all stochastic input variables showed that cooking temperature was the most influential parameter for reducing salmonellosis cases associated with WFGP meals, followed by storage temperature and Salmonella concentration on contaminated carcass surface before fabrication. The input variables were grouped to represent three main factors along the slaughter-to-table chain influencing Salmonella doses ingested via WFGP meals: DTLN-related factors, factors at processing other than DTLNs, and consumer-related factors. The evaluation of the impact of each group of factors by second-order Monte Carlo simulation showed that DTLN-related factors had the lowest impact on the risk estimate among the three groups of factors. These findings indicate that interventions to reduce Salmonella contamination in DTLNs or to remove DTLNs from WFGP products may be less critical for reducing human infections attributable to ground pork than improving consumers’ cooking habits or interventions of carcass decontamination at processing.

Original languageEnglish (US)
Pages (from-to)2237-2258
Number of pages22
JournalRisk Analysis
Volume39
Issue number10
DOIs
StatePublished - Oct 1 2019

Fingerprint

Salmonella Infections
Risk assessment
Lymph Nodes
Tissue
Salmonella
Cooking
Meals
Decontamination
Public health
Temperature
Processing
Red Meat
Sensitivity analysis
Contamination
Habits
Public Health
Fabrication
Infection

Keywords

  • Ground pork
  • Monte Carlo simulation
  • Salmonella
  • slaughterhouse-to-table pathway

ASJC Scopus subject areas

  • Safety, Risk, Reliability and Quality
  • Physiology (medical)

Cite this

Interventions Targeting Deep Tissue Lymph Nodes May Not Effectively Reduce the Risk of Salmonellosis from Ground Pork Consumption : A Quantitative Microbial Risk Assessment. / Zhang, Yangjunna; O'Connor, Annette M.; Wang, Chong; Dickson, James S.; Hurd, H. Scott; Wang, Bing.

In: Risk Analysis, Vol. 39, No. 10, 01.10.2019, p. 2237-2258.

Research output: Contribution to journalArticle

Zhang, Yangjunna ; O'Connor, Annette M. ; Wang, Chong ; Dickson, James S. ; Hurd, H. Scott ; Wang, Bing. / Interventions Targeting Deep Tissue Lymph Nodes May Not Effectively Reduce the Risk of Salmonellosis from Ground Pork Consumption : A Quantitative Microbial Risk Assessment. In: Risk Analysis. 2019 ; Vol. 39, No. 10. pp. 2237-2258.
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