Interleukin 8

Kathleen Brennan, Jialin C Zheng

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Citations (Scopus)

Abstract

Interleukin 8 (IL-8) is a chemotactic factor that attracts neutrophils, basophils, and T-cells during the inflammatory process. It is not a chemotactic factor for monocytes. IL-8 is involved in neutrophil activation, and is released from several cell types in response to inflammation, including monocytes, macrophages, neutrophils, and intestine, kidney, placenta, and bone marrow cells. It is a member of the beta-thromboglobulin superfamily and is structurally related to platelet factor 4. IL-8 is involved in mitogenesis, inhibition of angiogenesis, inflammation, chemotaxis, neutrophil degranulation, leukocyte activation, and calcium homeostasis. © 2007

Original languageEnglish (US)
Title of host publicationxPharm
Subtitle of host publicationThe Comprehensive Pharmacology Reference
PublisherElsevier Inc.
Pages1-4
Number of pages4
ISBN (Print)9780080552323
DOIs
StatePublished - Jan 1 2007

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Interleukin-8
Monocytes
Neutrophils
beta-Thromboglobulin
Inflammation
Platelet Factor 4
Neutrophil Activation
Basophils
Chemotactic Factors
Chemotaxis
Bone Marrow Cells
Placenta
Intestines
Leukocytes
Homeostasis
Macrophages
Calcium
T-Lymphocytes
Kidney

ASJC Scopus subject areas

  • Pharmacology, Toxicology and Pharmaceutics(all)

Cite this

Brennan, K., & Zheng, J. C. (2007). Interleukin 8. In xPharm: The Comprehensive Pharmacology Reference (pp. 1-4). Elsevier Inc.. https://doi.org/10.1016/B978-008055232-3.61916-6

Interleukin 8. / Brennan, Kathleen; Zheng, Jialin C.

xPharm: The Comprehensive Pharmacology Reference. Elsevier Inc., 2007. p. 1-4.

Research output: Chapter in Book/Report/Conference proceedingChapter

Brennan, K & Zheng, JC 2007, Interleukin 8. in xPharm: The Comprehensive Pharmacology Reference. Elsevier Inc., pp. 1-4. https://doi.org/10.1016/B978-008055232-3.61916-6
Brennan K, Zheng JC. Interleukin 8. In xPharm: The Comprehensive Pharmacology Reference. Elsevier Inc. 2007. p. 1-4 https://doi.org/10.1016/B978-008055232-3.61916-6
Brennan, Kathleen ; Zheng, Jialin C. / Interleukin 8. xPharm: The Comprehensive Pharmacology Reference. Elsevier Inc., 2007. pp. 1-4
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