Inter-vendor reproducibility of left and right ventricular cardiovascular magnetic resonance myocardial feature-tracking

Roman Johannes Gertz, Torben Lange, Johannes Tammo Kowallick, Sören Jan Backhaus, Michael Steinmetz, Wieland Staab, Shelby Kutty, Gerd Hasenfuß, Joachim Lotz, Andreas Schuster

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Aim: Since cardiovascular magnetic resonance feature-tracking (CMR-FT) has been demonstrated to be of incremental clinical merit we investigated the interchangeability of global left and right ventricular strain parameters between different CMR-FT software solutions. Material and methods: CMR-cine images of 10 patients without significant reduction in LVEF and RVEF and 10 patients with a significantly impaired systolic function were analyzed using two different types of FT-software (TomTec, Germany; QStrain, Netherlands). Global longitudinal strains (LV GLS, RV GLS), global left ventricular circumferential (GCS) and radial strains (GRS) were assessed. Differences in intra- and inter-observer variability within and between software types based on single and up to three repeated and subsequently averaged measurements were evaluated. Results: Inter-vendor agreement was highest for GCS followed by LV GLS. GRS and RV GLS showed lower inter-vendor agreement. Variability was consistently higher in healthy volunteers as compared to the patient group. Intra-vendor reproducibility was excellent for GCS, LV GLS and RV GLS, but lower for GRS. The impact of repeated measurements was most pronounced for GRS and RV GLS on an intra-vendor level. Conclusion: Cardiac pathology has no influence on CMR-FT reproducibility. LV GLS and GCS qualify as the most robust parameters within and between individual software types. Since both parameters can be interchangeably assessed with different software solutions they may enter the clinical arena for optimized diagnostic and prognostic evaluation of cardiovascular morbidity and mortality in various pathologies.

Original languageEnglish (US)
Article numbere0193746
JournalPloS one
Volume13
Issue number3
DOIs
StatePublished - Mar 2018

Fingerprint

Magnetic resonance
reproducibility
Magnetic Resonance Spectroscopy
Software
Pathology
Observer Variation
Netherlands
Germany
Healthy Volunteers
volunteers
morbidity
Morbidity
Mortality

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)

Cite this

Gertz, R. J., Lange, T., Kowallick, J. T., Backhaus, S. J., Steinmetz, M., Staab, W., ... Schuster, A. (2018). Inter-vendor reproducibility of left and right ventricular cardiovascular magnetic resonance myocardial feature-tracking. PloS one, 13(3), [e0193746]. https://doi.org/10.1371/journal.pone.0193746

Inter-vendor reproducibility of left and right ventricular cardiovascular magnetic resonance myocardial feature-tracking. / Gertz, Roman Johannes; Lange, Torben; Kowallick, Johannes Tammo; Backhaus, Sören Jan; Steinmetz, Michael; Staab, Wieland; Kutty, Shelby; Hasenfuß, Gerd; Lotz, Joachim; Schuster, Andreas.

In: PloS one, Vol. 13, No. 3, e0193746, 03.2018.

Research output: Contribution to journalArticle

Gertz, RJ, Lange, T, Kowallick, JT, Backhaus, SJ, Steinmetz, M, Staab, W, Kutty, S, Hasenfuß, G, Lotz, J & Schuster, A 2018, 'Inter-vendor reproducibility of left and right ventricular cardiovascular magnetic resonance myocardial feature-tracking', PloS one, vol. 13, no. 3, e0193746. https://doi.org/10.1371/journal.pone.0193746
Gertz, Roman Johannes ; Lange, Torben ; Kowallick, Johannes Tammo ; Backhaus, Sören Jan ; Steinmetz, Michael ; Staab, Wieland ; Kutty, Shelby ; Hasenfuß, Gerd ; Lotz, Joachim ; Schuster, Andreas. / Inter-vendor reproducibility of left and right ventricular cardiovascular magnetic resonance myocardial feature-tracking. In: PloS one. 2018 ; Vol. 13, No. 3.
@article{b7b42a81042c44079771b646bdce12bc,
title = "Inter-vendor reproducibility of left and right ventricular cardiovascular magnetic resonance myocardial feature-tracking",
abstract = "Aim: Since cardiovascular magnetic resonance feature-tracking (CMR-FT) has been demonstrated to be of incremental clinical merit we investigated the interchangeability of global left and right ventricular strain parameters between different CMR-FT software solutions. Material and methods: CMR-cine images of 10 patients without significant reduction in LVEF and RVEF and 10 patients with a significantly impaired systolic function were analyzed using two different types of FT-software (TomTec, Germany; QStrain, Netherlands). Global longitudinal strains (LV GLS, RV GLS), global left ventricular circumferential (GCS) and radial strains (GRS) were assessed. Differences in intra- and inter-observer variability within and between software types based on single and up to three repeated and subsequently averaged measurements were evaluated. Results: Inter-vendor agreement was highest for GCS followed by LV GLS. GRS and RV GLS showed lower inter-vendor agreement. Variability was consistently higher in healthy volunteers as compared to the patient group. Intra-vendor reproducibility was excellent for GCS, LV GLS and RV GLS, but lower for GRS. The impact of repeated measurements was most pronounced for GRS and RV GLS on an intra-vendor level. Conclusion: Cardiac pathology has no influence on CMR-FT reproducibility. LV GLS and GCS qualify as the most robust parameters within and between individual software types. Since both parameters can be interchangeably assessed with different software solutions they may enter the clinical arena for optimized diagnostic and prognostic evaluation of cardiovascular morbidity and mortality in various pathologies.",
author = "Gertz, {Roman Johannes} and Torben Lange and Kowallick, {Johannes Tammo} and Backhaus, {S{\"o}ren Jan} and Michael Steinmetz and Wieland Staab and Shelby Kutty and Gerd Hasenfu{\ss} and Joachim Lotz and Andreas Schuster",
year = "2018",
month = "3",
doi = "10.1371/journal.pone.0193746",
language = "English (US)",
volume = "13",
journal = "PLoS One",
issn = "1932-6203",
publisher = "Public Library of Science",
number = "3",

}

TY - JOUR

T1 - Inter-vendor reproducibility of left and right ventricular cardiovascular magnetic resonance myocardial feature-tracking

AU - Gertz, Roman Johannes

AU - Lange, Torben

AU - Kowallick, Johannes Tammo

AU - Backhaus, Sören Jan

AU - Steinmetz, Michael

AU - Staab, Wieland

AU - Kutty, Shelby

AU - Hasenfuß, Gerd

AU - Lotz, Joachim

AU - Schuster, Andreas

PY - 2018/3

Y1 - 2018/3

N2 - Aim: Since cardiovascular magnetic resonance feature-tracking (CMR-FT) has been demonstrated to be of incremental clinical merit we investigated the interchangeability of global left and right ventricular strain parameters between different CMR-FT software solutions. Material and methods: CMR-cine images of 10 patients without significant reduction in LVEF and RVEF and 10 patients with a significantly impaired systolic function were analyzed using two different types of FT-software (TomTec, Germany; QStrain, Netherlands). Global longitudinal strains (LV GLS, RV GLS), global left ventricular circumferential (GCS) and radial strains (GRS) were assessed. Differences in intra- and inter-observer variability within and between software types based on single and up to three repeated and subsequently averaged measurements were evaluated. Results: Inter-vendor agreement was highest for GCS followed by LV GLS. GRS and RV GLS showed lower inter-vendor agreement. Variability was consistently higher in healthy volunteers as compared to the patient group. Intra-vendor reproducibility was excellent for GCS, LV GLS and RV GLS, but lower for GRS. The impact of repeated measurements was most pronounced for GRS and RV GLS on an intra-vendor level. Conclusion: Cardiac pathology has no influence on CMR-FT reproducibility. LV GLS and GCS qualify as the most robust parameters within and between individual software types. Since both parameters can be interchangeably assessed with different software solutions they may enter the clinical arena for optimized diagnostic and prognostic evaluation of cardiovascular morbidity and mortality in various pathologies.

AB - Aim: Since cardiovascular magnetic resonance feature-tracking (CMR-FT) has been demonstrated to be of incremental clinical merit we investigated the interchangeability of global left and right ventricular strain parameters between different CMR-FT software solutions. Material and methods: CMR-cine images of 10 patients without significant reduction in LVEF and RVEF and 10 patients with a significantly impaired systolic function were analyzed using two different types of FT-software (TomTec, Germany; QStrain, Netherlands). Global longitudinal strains (LV GLS, RV GLS), global left ventricular circumferential (GCS) and radial strains (GRS) were assessed. Differences in intra- and inter-observer variability within and between software types based on single and up to three repeated and subsequently averaged measurements were evaluated. Results: Inter-vendor agreement was highest for GCS followed by LV GLS. GRS and RV GLS showed lower inter-vendor agreement. Variability was consistently higher in healthy volunteers as compared to the patient group. Intra-vendor reproducibility was excellent for GCS, LV GLS and RV GLS, but lower for GRS. The impact of repeated measurements was most pronounced for GRS and RV GLS on an intra-vendor level. Conclusion: Cardiac pathology has no influence on CMR-FT reproducibility. LV GLS and GCS qualify as the most robust parameters within and between individual software types. Since both parameters can be interchangeably assessed with different software solutions they may enter the clinical arena for optimized diagnostic and prognostic evaluation of cardiovascular morbidity and mortality in various pathologies.

UR - http://www.scopus.com/inward/record.url?scp=85043754871&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85043754871&partnerID=8YFLogxK

U2 - 10.1371/journal.pone.0193746

DO - 10.1371/journal.pone.0193746

M3 - Article

C2 - 29538467

AN - SCOPUS:85043754871

VL - 13

JO - PLoS One

JF - PLoS One

SN - 1932-6203

IS - 3

M1 - e0193746

ER -